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Structural basis for KCNE3 modulation of potassium recycling in epithelia

The single-span membrane protein KCNE3 modulates a variety of voltage-gated ion channels in diverse biological contexts. In epithelial cells, KCNE3 regulates the function of the KCNQ1 potassium ion (K(+)) channel to enable K(+) recycling coupled to transepithelial chloride ion (Cl(−)) secretion, a p...

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Detalles Bibliográficos
Autores principales: Kroncke, Brett M., Van Horn, Wade D., Smith, Jarrod, Kang, CongBao, Welch, Richard C., Song, Yuanli, Nannemann, David P., Taylor, Keenan C., Sisco, Nicholas J., George, Alfred L., Meiler, Jens, Vanoye, Carlos G., Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017827/
https://www.ncbi.nlm.nih.gov/pubmed/27626070
http://dx.doi.org/10.1126/sciadv.1501228

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