Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node

Lymph nodes (LNs) contain innate-like lymphocytes that survey the subcapsular sinus (SCS) and associated macrophages for pathogen entry. The factors promoting this surveillance behavior have not been defined. Here, we report that IL7R(hi)Ccr6(+) lymphocytes in mouse LNs rapidly produce IL17 upon bac...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Roth, Theodore L, Gray, Elizabeth E, Chen, Hsin, Rodda, Lauren B, Liang, Yin, Ventura, Patrick, Villeda, Saul, Crocker, Paul R, Cyster, Jason G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017864/
https://www.ncbi.nlm.nih.gov/pubmed/27487469
http://dx.doi.org/10.7554/eLife.18156

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