CRISPR-Cas9 directed knock-out of a constitutively expressed gene using lance array nanoinjection

BACKGROUND: CRISPR-Cas9 genome editing and labeling has emerged as an important tool in biologic research, particularly in regards to potential transgenic and gene therapy applications. Delivery of CRISPR-Cas9 plasmids to target cells is typically done by non-viral methods (chemical, physical, and/o...

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Detalles Bibliográficos
Autores principales: Sessions, John W., Skousen, Craig S., Price, Kevin D., Hanks, Brad W., Hope, Sandra, Alder, Jonathan K., Jensen, Brian D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017990/
https://www.ncbi.nlm.nih.gov/pubmed/27652094
http://dx.doi.org/10.1186/s40064-016-3037-0

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