Cargando…

T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report

BACKGROUND: Diffuse hepatic metastases with hepatic failure as a presentation of a T2 breast cancer is rare. This is also remarkable seeing our case had been on fertility treatments before presentation. There are no documented reports of breast cancer patient on fertility treatment presenting with d...

Descripción completa

Detalles Bibliográficos
Autor principal: Sule, Emmanuel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018071/
https://www.ncbi.nlm.nih.gov/pubmed/27614340
http://dx.doi.org/10.1016/j.ijscr.2016.06.031
_version_ 1782452853532524544
author Sule, Emmanuel A.
author_facet Sule, Emmanuel A.
author_sort Sule, Emmanuel A.
collection PubMed
description BACKGROUND: Diffuse hepatic metastases with hepatic failure as a presentation of a T2 breast cancer is rare. This is also remarkable seeing our case had been on fertility treatments before presentation. There are no documented reports of breast cancer patient on fertility treatment presenting with diffuse hepatic metastases and liver failure. CASE SUMMARY: A 41 year old Para 1 Nigerian woman being managed for secondary infertility with an extended use of clomiphene presented with a 3 months history of a left breast lump, nipple bleeding and later, yellowness of eyes, right hypochondrial pain malaise and drowsiness. Abdominal USS showed an enlarged liver with diffuse metastatic nodules. Liver function tests showed persistently elevating liver enzymes and serum bilirubin. Serology showed Hepatitis B negative. She was diagnosed with a T2 left invasive ductal carcinoma, Er−, Pr+ Her2+ with deteriorating liver function from diffuse hepatic metastases She had chemotherapy but succumbed barely a week of presentation. CONCLUSION: Breast cancer screening for patients before fertility treatments and continual surveillance while on such treatment is highly recommended.
format Online
Article
Text
id pubmed-5018071
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Elsevier
record_format MEDLINE/PubMed
spelling pubmed-50180712016-09-16 T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report Sule, Emmanuel A. Int J Surg Case Rep Case Report BACKGROUND: Diffuse hepatic metastases with hepatic failure as a presentation of a T2 breast cancer is rare. This is also remarkable seeing our case had been on fertility treatments before presentation. There are no documented reports of breast cancer patient on fertility treatment presenting with diffuse hepatic metastases and liver failure. CASE SUMMARY: A 41 year old Para 1 Nigerian woman being managed for secondary infertility with an extended use of clomiphene presented with a 3 months history of a left breast lump, nipple bleeding and later, yellowness of eyes, right hypochondrial pain malaise and drowsiness. Abdominal USS showed an enlarged liver with diffuse metastatic nodules. Liver function tests showed persistently elevating liver enzymes and serum bilirubin. Serology showed Hepatitis B negative. She was diagnosed with a T2 left invasive ductal carcinoma, Er−, Pr+ Her2+ with deteriorating liver function from diffuse hepatic metastases She had chemotherapy but succumbed barely a week of presentation. CONCLUSION: Breast cancer screening for patients before fertility treatments and continual surveillance while on such treatment is highly recommended. Elsevier 2016-07-28 /pmc/articles/PMC5018071/ /pubmed/27614340 http://dx.doi.org/10.1016/j.ijscr.2016.06.031 Text en © 2016 The Author(s) http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Sule, Emmanuel A.
T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title_full T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title_fullStr T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title_full_unstemmed T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title_short T2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. Cautionary report
title_sort t2 breast cancer presenting with diffuse liver metastases and hepatic failure following fertility treatment. cautionary report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018071/
https://www.ncbi.nlm.nih.gov/pubmed/27614340
http://dx.doi.org/10.1016/j.ijscr.2016.06.031
work_keys_str_mv AT suleemmanuela t2breastcancerpresentingwithdiffuselivermetastasesandhepaticfailurefollowingfertilitytreatmentcautionaryreport