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Primary Adenocarcinoma of an Ileostomy in Crohn's Disease

Although Crohn's disease has been associated with an increased risk of small bowel adenocarcinoma, primary adenocarcinoma arising from an ileostomy is a complication that has been rarely documented in Crohn's disease. Chronic small bowel inflammation may lead to development of malignancy t...

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Detalles Bibliográficos
Autores principales: Liu, Kevin, Prasad, Meena A., Lo, Amy, Bellaguarda, Emanuelle, Strong, Scott, Hanauer, Stephen B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Gastroenterology 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018220/
https://www.ncbi.nlm.nih.gov/pubmed/27622191
http://dx.doi.org/10.14309/crj.2016.85
Descripción
Sumario:Although Crohn's disease has been associated with an increased risk of small bowel adenocarcinoma, primary adenocarcinoma arising from an ileostomy is a complication that has been rarely documented in Crohn's disease. Chronic small bowel inflammation may lead to development of malignancy through the dysplasia-carcinoma sequence. We report a case of a 61-year-old woman with Crohn's ileocolitis diagnosed with a primary adenocarcinoma at the ileostomy with metastases to the liver 47 years after proctocolectomy, and review the literature.