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Cathepsin B Regulates Collagen Expression by Fibroblasts via Prolonging TLR2/NF-κB Activation

Fibroblasts are essential for tissue repair due to producing collagens, and lysosomal proteinase cathepsin B (CatB) is involved in promoting chronic inflammation. We herein report that CatB regulates the expression of collagens III and IV by fibroblasts in response to a TLR2 agonist, lipopolysacchar...

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Detalles Bibliográficos
Autores principales:	Li, Xue, Wu, Zhou, Ni, Junjun, Liu, Yicong, Meng, Jie, Yu, Weixian, Nakanishi, Hiroshi, Zhou, Yanmin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018341/ https://www.ncbi.nlm.nih.gov/pubmed/27648120 http://dx.doi.org/10.1155/2016/7894247

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