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UniCon3D: de novo protein structure prediction using united-residue conformational search via stepwise, probabilistic sampling

Motivation: Recent experimental studies have suggested that proteins fold via stepwise assembly of structural units named ‘foldons’ through the process of sequential stabilization. Alongside, latest developments on computational side based on probabilistic modeling have shown promising direction to...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Debswapna, Cao, Renzhi, Cheng, Jianlin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018369/
https://www.ncbi.nlm.nih.gov/pubmed/27259540
http://dx.doi.org/10.1093/bioinformatics/btw316