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Weighted mutual information analysis substantially improves domain-based functional network models
Motivation: Functional protein–protein interaction (PPI) networks elucidate molecular pathways underlying complex phenotypes, including those of human diseases. Extrapolation of domain–domain interactions (DDIs) from known PPIs is a major domain-based method for inferring functional PPI networks. Ho...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018372/ https://www.ncbi.nlm.nih.gov/pubmed/27207946 http://dx.doi.org/10.1093/bioinformatics/btw320 |