Cargando…

Glucagon-Like Peptide-1 Excites Firing and Increases GABAergic Miniature Postsynaptic Currents (mPSCs) in Gonadotropin-Releasing Hormone (GnRH) Neurons of the Male Mice via Activation of Nitric Oxide (NO) and Suppression of Endocannabinoid Signaling Pathways

Glucagon-like peptide-1 (GLP-1), a metabolic signal molecule, regulates reproduction, although, the involved molecular mechanisms have not been elucidated, yet. Therefore, responsiveness of gonadotropin-releasing hormone (GnRH) neurons to the GLP-1 analog Exendin-4 and elucidation of molecular pathw...

Descripción completa

Detalles Bibliográficos
Autores principales:	Farkas, Imre, Vastagh, Csaba, Farkas, Erzsébet, Bálint, Flóra, Skrapits, Katalin, Hrabovszky, Erik, Fekete, Csaba, Liposits, Zsolt
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018486/ https://www.ncbi.nlm.nih.gov/pubmed/27672360 http://dx.doi.org/10.3389/fncel.2016.00214

Ejemplares similares

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner
por: Farkas, Imre, et al.
Publicado: (2013)

Estradiol Increases Glutamate and GABA Neurotransmission into GnRH Neurons via Retrograde NO-Signaling in Proestrous Mice during the Positive Estradiol Feedback Period
por: Farkas, Imre, et al.
Publicado: (2018)

Secretin Regulates Excitatory GABAergic Neurotransmission to GnRH Neurons via Retrograde NO Signaling Pathway in Mice
por: Csillag, Veronika, et al.
Publicado: (2019)

Retrograde Endocannabinoid Signaling Reduces GABAergic Synaptic Transmission to Gonadotropin-Releasing Hormone Neurons
por: Farkas, Imre, et al.
Publicado: (2010)

Proestrus Differentially Regulates Expression of Ion Channel and Calcium Homeostasis Genes in GnRH Neurons of Mice
por: Vastagh, Csaba, et al.
Publicado: (2019)

Networking of glucagon-like peptide-1 axons with GnRH neurons in the basal forebrain of male mice revealed by 3DISCO-based immunocytochemistry and optogenetics
por: Vastagh, Csaba, et al.
Publicado: (2020)

Altered Expression of Genes Encoding Neurotransmitter Receptors in GnRH Neurons of Proestrous Mice
por: Vastagh, Csaba, et al.
Publicado: (2016)

Gonadal Cycle-Dependent Expression of Genes Encoding Peptide-, Growth Factor-, and Orphan G-Protein-Coupled Receptors in Gonadotropin- Releasing Hormone Neurons of Mice
por: Vastagh, Csaba, et al.
Publicado: (2021)

GnRH Neurons Provide Direct Input to Hypothalamic Tyrosine Hydroxylase Immunoreactive Neurons Which Is Maintained During Lactation
por: Bardóczi, Zsuzsanna, et al.
Publicado: (2018)

Endocannabinoid and nitric oxide systems of the hypothalamic paraventricular nucleus mediate effects of NPY on energy expenditure
por: Péterfi, Zoltán, et al.
Publicado: (2018)

Area-specific analysis of the distribution of hypothalamic neurons projecting to the rat ventral tegmental area, with special reference to the GABAergic and glutamatergic efferents
por: Kalló, Imre, et al.
Publicado: (2015)

Gonadotropin-Releasing Hormone (GnRH) Receptor Structure and GnRH Binding
por: Flanagan, Colleen A., et al.
Publicado: (2017)

Gonadotropin-Releasing Hormone (GnRH)/GnRH Receptors and Their Role in the Treatment of Endometriosis
por: Resta, Christina, et al.
Publicado: (2023)

Estrogen Receptor Beta and 2-arachidonoylglycerol Mediate the Suppressive Effects of Estradiol on Frequency of Postsynaptic Currents in Gonadotropin-Releasing Hormone Neurons of Metestrous Mice: An Acute Slice Electrophysiological Study
por: Bálint, Flóra, et al.
Publicado: (2016)

The cryptic gonadotropin-releasing hormone neuronal system of human basal ganglia
por: Skrapits, Katalin, et al.
Publicado: (2021)

Changes in GABAergic Transmission to and Intrinsic Excitability of Gonadotropin-Releasing Hormone (GnRH) Neurons during the Estrous Cycle in Mice
por: Adams, Caroline, et al.
Publicado: (2018)

Robust GABAergic Regulation of the GnRH Neuron Distal Dendron
por: Liu, Xinhuai, et al.
Publicado: (2022)

Divergent expression patterns of pituitary gonadotropin subunit and GnRH receptor genes to continuous GnRH in vitro and in vivo
por: Janjic, Marija M., et al.
Publicado: (2019)

Role of gonadotropin-releasing hormone (GnRH) in ovarian cancer
por: Gründker, Carsten, et al.
Publicado: (2003)

The Role of Gonadotropin-Releasing Hormone (GnRH) in Endometrial Cancer
por: Emons, Günter, et al.
Publicado: (2021)

Role of Gonadotropin-Releasing Hormone (GnRH) in Ovarian Cancer
por: Gründker, Carsten, et al.
Publicado: (2021)

Impact of Proestrus on Gene Expression in the Medial Preoptic Area of Mice
por: Vastagh, Csaba, et al.
Publicado: (2017)

Gonadotropin-releasing hormone (GnRH) stimulation test before and after GnRH analogue treatment in central precocious puberty; can GnRH test simplify adequately?
por: Yang, You Jean, et al.
Publicado: (2013)

Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human
por: Hrabovszky, Erik, et al.
Publicado: (2013)

Ovarian Hyper-Response to Administration of an GnRH-Agonist Without Gonadotropins
por: Park, Hyun Tae, et al.
Publicado: (2011)

Endocannabinoids and Endovanilloids: A Possible Balance in the Regulation of the Testicular GnRH Signalling
por: Chianese, Rosanna, et al.
Publicado: (2013)

Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling: DOES THE ERK SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?
por: Armstrong, Stephen P., et al.
Publicado: (2010)

Lateral hypothalamic orexin and melanin-concentrating hormone neurons provide direct input to gonadotropin-releasing hormone neurons in the human
por: Skrapits, Katalin, et al.
Publicado: (2015)

Gonadotropin Releasing Hormone (GnRH) Triggers Neurogenesis in the Hypothalamus of Adult Zebrafish
por: Ceriani, Ricardo, et al.
Publicado: (2021)

Local Duplication of Gonadotropin-Releasing Hormone (GnRH) Receptor before Two Rounds of Whole Genome Duplication and Origin of the Mammalian GnRH Receptor
por: Sefideh, Fatemeh Ameri, et al.
Publicado: (2014)

Double-edged sword of gonadotropin-releasing hormone (GnRH): A novel role of GnRH in the multiple beneficial functions of endometrial stem cells
por: Park, Se-Ra, et al.
Publicado: (2018)

Pulsatile and Sustained Gonadotropin-releasing Hormone (GnRH) Receptor Signaling: DOES THE Ca(2+)/NFAT SIGNALING PATHWAY DECODE GnRH PULSE FREQUENCY?
por: Armstrong, Stephen P., et al.
Publicado: (2009)

Mixed mode oscillations in a gonadotropin-releasing hormone (GnRH) neuron model
por: Banerjee, Sayanti, et al.
Publicado: (2010)

Small molecule piperazinyl-benzimidazole antagonists of the gonadotropin-releasing hormone (GnRH) receptor
por: Fjellaksel, Richard, et al.
Publicado: (2017)

Effect of Inflammation on Female Gonadotropin-Releasing Hormone (GnRH) Neurons: Mechanisms and Consequences
por: Barabás, Klaudia, et al.
Publicado: (2020)

A Novel Nomogram for Individualized Gonadotropin Starting Dose in GnRH Antagonist Protocol
por: Li, Yubin, et al.
Publicado: (2021)

Microdose Flare-up Gonadotropin-releasing Hormone (GnRH) Agonist Versus GnRH Antagonist Protocols in Poor Ovarian Responders Undergoing Intracytoplasmic Sperm Injection
por: Boza, Aysen, et al.
Publicado: (2016)

Mechanisms of Reciprocal Regulation of Gonadotropin-Releasing Hormone (GnRH)-Producing and Immune Systems: The Role of GnRH, Cytokines and Their Receptors in Early Ontogenesis in Normal and Pathological Conditions
por: Zakharova, Liudmila, et al.
Publicado: (2020)

Zebrafish adult-derived hypothalamic neurospheres generate gonadotropin-releasing hormone (GnRH) neurons
por: Cortés-Campos, Christian, et al.
Publicado: (2015)

Characterization of Gonadotropin-Releasing Hormone (GnRH) Genes From Cartilaginous Fish: Evolutionary Perspectives
por: Gaillard, Anne-Laure, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_dhmaiq8j3urmnsdgi248vi9pf0