Cargando…

Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA

PURPOSE: Well-known defect of TG-43 based algorithms used in brachytherapy is a lack of information about interaction cross-sections, which are determined not only by electron density but also by atomic number. TG-186 recommendations with using of MBDCA (model-based dose calculation algorithm), accu...

Descripción completa

Detalles Bibliográficos
Autores principales: Zwierzchowski, Grzegorz, Bielęda, Grzegorz, Skowronek, Janusz, Mazur, Magdalena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Termedia Publishing House 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018527/
https://www.ncbi.nlm.nih.gov/pubmed/27648087
http://dx.doi.org/10.5114/jcb.2016.61828
_version_ 1782452923945451520
author Zwierzchowski, Grzegorz
Bielęda, Grzegorz
Skowronek, Janusz
Mazur, Magdalena
author_facet Zwierzchowski, Grzegorz
Bielęda, Grzegorz
Skowronek, Janusz
Mazur, Magdalena
author_sort Zwierzchowski, Grzegorz
collection PubMed
description PURPOSE: Well-known defect of TG-43 based algorithms used in brachytherapy is a lack of information about interaction cross-sections, which are determined not only by electron density but also by atomic number. TG-186 recommendations with using of MBDCA (model-based dose calculation algorithm), accurate tissues segmentation, and the structure's elemental composition continue to create difficulties in brachytherapy dosimetry. For the clinical use of new algorithms, it is necessary to introduce reliable and repeatable methods of treatment planning systems (TPS) verification. The aim of this study is the verification of calculation algorithm used in TPS for shielded vaginal applicators as well as developing verification procedures for current and further use, based on the film dosimetry method. MATERIAL AND METHODS: Calibration data was collected by separately irradiating 14 sheets of Gafchromic(®) EBT films with the doses from 0.25 Gy to 8.0 Gy using HDR (192)Ir source. Standard vaginal cylinders of three diameters were used in the water phantom. Measurements were performed without any shields and with three shields combination. Gamma analyses were performed using the VeriSoft(®) package. RESULTS: Calibration curve was determined as third-degree polynomial type. For all used diameters of unshielded cylinder and for all shields combinations, Gamma analysis were performed and showed that over 90% of analyzed points meets Gamma criteria (3%, 3 mm). CONCLUSIONS: Gamma analysis showed good agreement between dose distributions calculated using TPS and measured by Gafchromic films, thus showing the viability of using film dosimetry in brachytherapy.
format Online
Article
Text
id pubmed-5018527
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Termedia Publishing House
record_format MEDLINE/PubMed
spelling pubmed-50185272016-09-19 Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA Zwierzchowski, Grzegorz Bielęda, Grzegorz Skowronek, Janusz Mazur, Magdalena J Contemp Brachytherapy Original Paper PURPOSE: Well-known defect of TG-43 based algorithms used in brachytherapy is a lack of information about interaction cross-sections, which are determined not only by electron density but also by atomic number. TG-186 recommendations with using of MBDCA (model-based dose calculation algorithm), accurate tissues segmentation, and the structure's elemental composition continue to create difficulties in brachytherapy dosimetry. For the clinical use of new algorithms, it is necessary to introduce reliable and repeatable methods of treatment planning systems (TPS) verification. The aim of this study is the verification of calculation algorithm used in TPS for shielded vaginal applicators as well as developing verification procedures for current and further use, based on the film dosimetry method. MATERIAL AND METHODS: Calibration data was collected by separately irradiating 14 sheets of Gafchromic(®) EBT films with the doses from 0.25 Gy to 8.0 Gy using HDR (192)Ir source. Standard vaginal cylinders of three diameters were used in the water phantom. Measurements were performed without any shields and with three shields combination. Gamma analyses were performed using the VeriSoft(®) package. RESULTS: Calibration curve was determined as third-degree polynomial type. For all used diameters of unshielded cylinder and for all shields combinations, Gamma analysis were performed and showed that over 90% of analyzed points meets Gamma criteria (3%, 3 mm). CONCLUSIONS: Gamma analysis showed good agreement between dose distributions calculated using TPS and measured by Gafchromic films, thus showing the viability of using film dosimetry in brachytherapy. Termedia Publishing House 2016-08-16 2016-08 /pmc/articles/PMC5018527/ /pubmed/27648087 http://dx.doi.org/10.5114/jcb.2016.61828 Text en Copyright: © 2016 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
spellingShingle Original Paper
Zwierzchowski, Grzegorz
Bielęda, Grzegorz
Skowronek, Janusz
Mazur, Magdalena
Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title_full Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title_fullStr Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title_full_unstemmed Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title_short Film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of MBDCA
title_sort film based verification of calculation algorithms used for brachytherapy planning-getting ready for upcoming challenges of mbdca
topic Original Paper
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018527/
https://www.ncbi.nlm.nih.gov/pubmed/27648087
http://dx.doi.org/10.5114/jcb.2016.61828
work_keys_str_mv AT zwierzchowskigrzegorz filmbasedverificationofcalculationalgorithmsusedforbrachytherapyplanninggettingreadyforupcomingchallengesofmbdca
AT bieledagrzegorz filmbasedverificationofcalculationalgorithmsusedforbrachytherapyplanninggettingreadyforupcomingchallengesofmbdca
AT skowronekjanusz filmbasedverificationofcalculationalgorithmsusedforbrachytherapyplanninggettingreadyforupcomingchallengesofmbdca
AT mazurmagdalena filmbasedverificationofcalculationalgorithmsusedforbrachytherapyplanninggettingreadyforupcomingchallengesofmbdca