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ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy)
PURPOSE: Aim of the COBRA (Consortium for Brachytherapy Data Analysis) project is to create a multicenter group (consortium) and a web-based system for standardized data collection. MATERIAL AND METHODS: GEC-ESTRO (Groupe Européen de Curiethérapie – European Society for Radiotherapy & Oncology)...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018530/ https://www.ncbi.nlm.nih.gov/pubmed/27648088 http://dx.doi.org/10.5114/jcb.2016.61958 |
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author | Tagliaferri, Luca Kovács, György Autorino, Rosa Budrukkar, Ashwini Guinot, Jose Luis Hildebrand, Guido Johansson, Bengt Monge, Rafael Martìnez Meyer, Jens E. Niehoff, Peter Rovirosa, Angeles Takàcsi-Nagy, Zoltàn Dinapoli, Nicola Lanzotti, Vito Damiani, Andrea Soror, Tamer Valentini, Vincenzo |
author_facet | Tagliaferri, Luca Kovács, György Autorino, Rosa Budrukkar, Ashwini Guinot, Jose Luis Hildebrand, Guido Johansson, Bengt Monge, Rafael Martìnez Meyer, Jens E. Niehoff, Peter Rovirosa, Angeles Takàcsi-Nagy, Zoltàn Dinapoli, Nicola Lanzotti, Vito Damiani, Andrea Soror, Tamer Valentini, Vincenzo |
author_sort | Tagliaferri, Luca |
collection | PubMed |
description | PURPOSE: Aim of the COBRA (Consortium for Brachytherapy Data Analysis) project is to create a multicenter group (consortium) and a web-based system for standardized data collection. MATERIAL AND METHODS: GEC-ESTRO (Groupe Européen de Curiethérapie – European Society for Radiotherapy & Oncology) Head and Neck (H&N) Working Group participated in the project and in the implementation of the consortium agreement, the ontology (data-set) and the necessary COBRA software services as well as the peer reviewing of the general anatomic site-specific COBRA protocol. The ontology was defined by a multicenter task-group. RESULTS: Eleven centers from 6 countries signed an agreement and the consortium approved the ontology. We identified 3 tiers for the data set: Registry (epidemiology analysis), Procedures (prediction models and DSS), and Research (radiomics). The COBRA-Storage System (C-SS) is not time-consuming as, thanks to the use of “brokers”, data can be extracted directly from the single center's storage systems through a connection with “structured query language database” (SQL-DB), Microsoft Access(®), FileMaker Pro(®), or Microsoft Excel(®). The system is also structured to perform automatic archiving directly from the treatment planning system or afterloading machine. The architecture is based on the concept of “on-purpose data projection”. The C-SS architecture is privacy protecting because it will never make visible data that could identify an individual patient. This C-SS can also benefit from the so called “distributed learning” approaches, in which data never leave the collecting institution, while learning algorithms and proposed predictive models are commonly shared. CONCLUSIONS: Setting up a consortium is a feasible and practicable tool in the creation of an international and multi-system data sharing system. COBRA C-SS seems to be well accepted by all involved parties, primarily because it does not influence the center's own data storing technologies, procedures, and habits. Furthermore, the method preserves the privacy of all patients. |
format | Online Article Text |
id | pubmed-5018530 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-50185302016-09-19 ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) Tagliaferri, Luca Kovács, György Autorino, Rosa Budrukkar, Ashwini Guinot, Jose Luis Hildebrand, Guido Johansson, Bengt Monge, Rafael Martìnez Meyer, Jens E. Niehoff, Peter Rovirosa, Angeles Takàcsi-Nagy, Zoltàn Dinapoli, Nicola Lanzotti, Vito Damiani, Andrea Soror, Tamer Valentini, Vincenzo J Contemp Brachytherapy Review Paper PURPOSE: Aim of the COBRA (Consortium for Brachytherapy Data Analysis) project is to create a multicenter group (consortium) and a web-based system for standardized data collection. MATERIAL AND METHODS: GEC-ESTRO (Groupe Européen de Curiethérapie – European Society for Radiotherapy & Oncology) Head and Neck (H&N) Working Group participated in the project and in the implementation of the consortium agreement, the ontology (data-set) and the necessary COBRA software services as well as the peer reviewing of the general anatomic site-specific COBRA protocol. The ontology was defined by a multicenter task-group. RESULTS: Eleven centers from 6 countries signed an agreement and the consortium approved the ontology. We identified 3 tiers for the data set: Registry (epidemiology analysis), Procedures (prediction models and DSS), and Research (radiomics). The COBRA-Storage System (C-SS) is not time-consuming as, thanks to the use of “brokers”, data can be extracted directly from the single center's storage systems through a connection with “structured query language database” (SQL-DB), Microsoft Access(®), FileMaker Pro(®), or Microsoft Excel(®). The system is also structured to perform automatic archiving directly from the treatment planning system or afterloading machine. The architecture is based on the concept of “on-purpose data projection”. The C-SS architecture is privacy protecting because it will never make visible data that could identify an individual patient. This C-SS can also benefit from the so called “distributed learning” approaches, in which data never leave the collecting institution, while learning algorithms and proposed predictive models are commonly shared. CONCLUSIONS: Setting up a consortium is a feasible and practicable tool in the creation of an international and multi-system data sharing system. COBRA C-SS seems to be well accepted by all involved parties, primarily because it does not influence the center's own data storing technologies, procedures, and habits. Furthermore, the method preserves the privacy of all patients. Termedia Publishing House 2016-08-26 2016-08 /pmc/articles/PMC5018530/ /pubmed/27648088 http://dx.doi.org/10.5114/jcb.2016.61958 Text en Copyright: © 2016 Termedia Sp. z o. o. http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License, allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Review Paper Tagliaferri, Luca Kovács, György Autorino, Rosa Budrukkar, Ashwini Guinot, Jose Luis Hildebrand, Guido Johansson, Bengt Monge, Rafael Martìnez Meyer, Jens E. Niehoff, Peter Rovirosa, Angeles Takàcsi-Nagy, Zoltàn Dinapoli, Nicola Lanzotti, Vito Damiani, Andrea Soror, Tamer Valentini, Vincenzo ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title | ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title_full | ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title_fullStr | ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title_full_unstemmed | ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title_short | ENT COBRA (Consortium for Brachytherapy Data Analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
title_sort | ent cobra (consortium for brachytherapy data analysis): interdisciplinary standardized data collection system for head and neck patients treated with interventional radiotherapy (brachytherapy) |
topic | Review Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018530/ https://www.ncbi.nlm.nih.gov/pubmed/27648088 http://dx.doi.org/10.5114/jcb.2016.61958 |
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