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Overproduction of reactive oxygen species - obligatory or not for induction of apoptosis by anticancer drugs
Many studies demonstrate that conventional anticancer drugs elevate intracellular level of reactive oxygen species (ROS) and alter redox-homeostasis of cancer cells. It is widely accepted that anticancer effect of these chemotherapeutics is due to induction of oxidative stress and ROS-mediated apopt...
Autores principales: | Ivanova, Donika, Zhelev, Zhivko, Aoki, Ichio, Bakalova, Rumiana, Higashi, Tatsuya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018533/ https://www.ncbi.nlm.nih.gov/pubmed/27647966 http://dx.doi.org/10.21147/j.issn.1000-9604.2016.04.01 |
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