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A phase I trial of an oral subtype-selective histone deacetylase inhibitor, chidamide, in combination with paclitaxel and carboplatin in patients with advanced non-small cell lung cancer

OBJECTIVE: This phase I study was to evaluate safety, maximum tolerated dose, pharmacokinetics and preliminary antitumor activity of chidamide, a novel subtype-selective histone deacetylase (HDAC) inhibitor, in combination with paclitaxel and carboplatin in patients with advanced non-small cell lung...

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Detalles Bibliográficos
Autores principales:	Hu, Xingsheng, Wang, Lin, Lin, Lin, Han, Xiaohong, Dou, Guifang, Meng, Zhiyun, Shi, Yuankai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AME Publishing Company 2016
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018540/ https://www.ncbi.nlm.nih.gov/pubmed/27647973 http://dx.doi.org/10.21147/j.issn.1000-9604.2016.04.08

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