Plasmodium falciparum Choline Kinase Inhibition Leads to a Major Decrease in Phosphatidylethanolamine Causing Parasite Death

Malaria is a life-threatening disease caused by different species of the protozoan parasite Plasmodium, with P. falciparum being the deadliest. Increasing parasitic resistance to existing antimalarials makes the necessity of novel avenues to treat this disease an urgent priority. The enzymes respons...

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Detalles Bibliográficos
Autores principales: Serrán-Aguilera, Lucía, Denton, Helen, Rubio-Ruiz, Belén, López-Gutiérrez, Borja, Entrena, Antonio, Izquierdo, Luis, Smith, Terry K., Conejo-García, Ana, Hurtado-Guerrero, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018819/
https://www.ncbi.nlm.nih.gov/pubmed/27616047
http://dx.doi.org/10.1038/srep33189

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