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Sustained elevation of NF-κB activity sensitizes offspring of maternal inflammation to hypertension via impairing PGC-1α recovery
Growing evidence has demonstrated that maternal detrimental factors, including inflammation, contribute to the development of hypertension in the offspring. The current study found that offspring subjected to prenatal exposure of inflammation by lipopolysaccharide (LPS) challenge during the second s...
Autores principales: | Deng, Yafei, Zhang, Qi, Luo, Hongqin, Chen, Xianhua, Han, Qi, Wang, Fangjie, Huang, Pei, Lai, Wenjing, Guan, Xiao, Pan, Xiaodong, Ji, Yan, Guo, Wei, Che, Ling, Tang, Yuan, Gu, Liangqi, Yu, Jianhua, Namaka, Michael, Deng, Youcai, Li, Xiaohui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018852/ https://www.ncbi.nlm.nih.gov/pubmed/27616627 http://dx.doi.org/10.1038/srep32642 |
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