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Promoter hypermethylation of KLOTHO; an anti-senescence related gene in colorectal cancer patients of Kashmir valley

Hypermethylation of CpG islands located in the promoter regions of genes is a major event in the development of the majority of cancer types, due to the subsequent aberrant silencing of important tumor suppressor genes. KLOTHO; a novel gene associated primarily with suppressing senescence has been s...

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Detalles Bibliográficos
Autores principales: Perveez, Malik, Ajaz, Malik, Afroze, Dil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019213/
https://www.ncbi.nlm.nih.gov/pubmed/27844013