Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation

Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number...

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Detalles Bibliográficos
Autores principales: Ahrari, Sajjad, Mogharrab, Navid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019223/
https://www.ncbi.nlm.nih.gov/pubmed/27843979
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author Ahrari, Sajjad
Mogharrab, Navid
author_facet Ahrari, Sajjad
Mogharrab, Navid
author_sort Ahrari, Sajjad
collection PubMed
description Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of virulent effects of Helicobacter pyloriββαβββ
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spelling pubmed-50192232016-11-14 Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation Ahrari, Sajjad Mogharrab, Navid Mol Biol Res Commun Original Article Microtubule Affinity-Regulating Kinase 2 (MARK2) protein has a substantial role in regulation of vital cellular processes like induction of polarity, regulation of cell junctions, cytoskeleton structure and cell differentiation. The abnormal function of this protein has been associated with a number of pathological conditions like Alzheimer disease, autism, several carcinomas and development of virulent effects of Helicobacter pyloriββαβββ Shiraz University 2014-09 /pmc/articles/PMC5019223/ /pubmed/27843979 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Ahrari, Sajjad
Mogharrab, Navid
Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title_full Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title_fullStr Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title_full_unstemmed Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title_short Effects of T208E activating mutation on MARK2 protein structure and dynamics: Modeling and simulation
title_sort effects of t208e activating mutation on mark2 protein structure and dynamics: modeling and simulation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019223/
https://www.ncbi.nlm.nih.gov/pubmed/27843979
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