Cargando…

Gene variance in the nicotinic receptor cluster (CHRNA5‐CHRNA3‐CHRNB4) predicts death from cardiopulmonary disease and cancer in smokers

BACKGROUND: Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5‐CHRNA3‐CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking‐related diseases such as chronic obstructive pulmonary disea...

Descripción completa

Detalles Bibliográficos
Autores principales:	Halldén, S., Sjögren, M., Hedblad, B., Engström, G., Hamrefors, V., Manjer, J., Melander, O.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019278/ https://www.ncbi.nlm.nih.gov/pubmed/26689306 http://dx.doi.org/10.1111/joim.12454

Ejemplares similares

Association and cis-mQTL analysis of variants in CHRNA3-A5, CHRNA7, CHRNB2, and CHRNB4 in relation to nicotine dependence in a Chinese Han population
por: Liu, Qiang, et al.
Publicado: (2018)

Significant association of the CHRNB3-CHRNA6 gene cluster with nicotine dependence in the Chinese Han population
por: Wen, Li, et al.
Publicado: (2017)

Study on polymorphisms in CHRNA5/CHRNA3/CHRNB4 gene cluster and the associated with the risk of non-small cell lung cancer
por: Sun, Yiting, et al.
Publicado: (2017)

Genetic variation at CHRNA5-CHRNA3-CHRNB4 interacts with smoking status to influence body mass index
por: Freathy, Rachel M, et al.
Publicado: (2011)

A common genetic variant in the 15q24 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) is associated with a reduced ability of women to quit smoking in pregnancy
por: Freathy, Rachel M., et al.
Publicado: (2009)

Crucial roles of the CHRNB3–CHRNA6 gene cluster on chromosome 8 in nicotine dependence: update and subjects for future research
por: Wen, L, et al.
Publicado: (2016)

Genetic Association of CHRNB3 and CHRNA6 Gene Polymorphisms with Nicotine Dependence Syndrome Scale in Korean Population
por: Won, Wang-Youn, et al.
Publicado: (2014)

Genetic variation in the 15q25 nicotinic acetylcholine receptor gene cluster (CHRNA5–CHRNA3–CHRNB4) interacts with maternal self-reported smoking status during pregnancy to influence birth weight
por: Tyrrell, Jessica, et al.
Publicado: (2012)

Association of Polymorphism CHRNA5 and CHRNA3 Gene in People Addicted to Nicotine
por: Chmielowiec, Krzysztof, et al.
Publicado: (2022)

CHRNA5 rs16969968 and CHRNA3 rs578776 polymorphisms are associated with multiple nicotine dependence phenotypes in Bangladeshi smokers
por: Chaity, Nusrat Islam, et al.
Publicado: (2022)

Associations between Variation in CHRNA5-CHRNA3-CHRNB4, Body Mass Index and Blood Pressure in the Northern Finland Birth Cohort 1966
por: Kaakinen, Marika, et al.
Publicado: (2012)

Association Between CHRNA3 and CHRNA5 Nicotine Receptor Subunit Gene Variants and Nicotine Dependence in an Isolated Populationof Kashubians in Poland
por: Kita-Milczarska, Karolina, et al.
Publicado: (2016)

O015. Evaluation of the genetic polymorphism of the α3 (CHRNA3) and α5 (CHRNA5) nicotinic receptor subunits, in patients with cluster headache
por: Cainazzo, Maria Michela, et al.
Publicado: (2015)

Variants near CHRNB3-CHRNA6 are associated with DSM-5 cocaine use disorder: evidence for pleiotropy
por: Sadler, Brooke, et al.
Publicado: (2014)

Nicotinic Receptor Gene CHRNA4 Interacts with Processing Load in Attention
por: Espeseth, Thomas, et al.
Publicado: (2010)

In Vitro and Ex Vivo Analysis of CHRNA3 and CHRNA5 Haplotype Expression
por: Doyle, Glenn A., et al.
Publicado: (2011)

From Men to Mice: CHRNA5/CHRNA3, Smoking Behavior and Disease
por: Ware, Jennifer J., et al.
Publicado: (2012)

CHRNA5 and CHRNA3 polymorphism and lung cancer susceptibility in Palestinian population
por: Ayesh, Basim Mohammad, et al.
Publicado: (2018)

Combined genetic influence of the nicotinic receptor gene cluster CHRNA5/A3/B4 on nicotine dependence
por: Lee, Sung-Ha, et al.
Publicado: (2018)

Chromosome 15q25 (CHRNA3-CHRNB4) Variation Indirectly Impacts Lung Cancer Risk in Chinese Males
por: Zhang, Yalei, et al.
Publicado: (2016)

CHRNA5/CHRNA3 gene cluster is a risk factor for lumbar disc herniation: a case-control study
por: Yang, Xuejun, et al.
Publicado: (2019)

Genetic Modifiers of Oral Nicotine Consumption in Chrna5 Null Mutant Mice
por: Meyers, Erin, et al.
Publicado: (2021)

Chromosome 15q25 (CHRNA3-CHRNA5) Variation Impacts Indirectly on Lung Cancer Risk
por: Wang, Yufei, et al.
Publicado: (2011)

Polymorphisms of CHRNA3 and CHRNA5: Head and neck cancer and cigarette consumption intensity in a Brazilian population
por: Silva, Mariana R., et al.
Publicado: (2019)

The CHRNA3 rs578776 Variant is Associated with an Intrinsic Reward Sensitivity Deficit in Smokers
por: Robinson, Jason D., et al.
Publicado: (2013)

Genetic variants of CHRNA5-A3 and CHRNB3-A6 predict survival of patients with advanced non-small cell lung cancer
por: Wang, Yang, et al.
Publicado: (2016)

Association of the CHRNA4 Neuronal Nicotinic Receptor Subunit Gene with Frequency of Binge Drinking in Young Adults
por: Coon, Hilary, et al.
Publicado: (2014)

Association of the Nicotinic Receptor α7 Subunit Gene (CHRNA7) with Schizophrenia and Visual Backward Masking
por: Bakanidze, George, et al.
Publicado: (2013)

Financial and Psychological Risk Attitudes Associated with Two Single Nucleotide Polymorphisms in the Nicotine Receptor (CHRNA4) Gene
por: Roe, Brian E., et al.
Publicado: (2009)

Massive Withdrawal Symptoms and Affective Vulnerability Are Associated with Variants of the CHRNA4 Gene in a Subgroup of Smokers
por: Lazary, Judit, et al.
Publicado: (2014)

Genetic Association Study of the Alpha 7 Nicotinic Receptor (CHRNA7) with the Development of Schizophrenia and Bipolar Disorder in Korean Population
por: Joo, Eun-Jeong, et al.
Publicado: (2010)

Smoking Interacts With CHRNA5, a Nicotinic Acetylcholine Receptor Subunit Gene, to Influence the Risk of IBD-Related Surgery
por: Cushing, Kelly C, et al.
Publicado: (2018)

Chronic Obstructive Pulmonary Disease Risk and Smoking Cessation Changes Induced by CHRNA5-A3 and CHRNB3-A6 Variation in a Chinese Male Population
por: Zhao, L, et al.
Publicado: (2019)

CHRNA7 Polymorphisms and Response to Cholinesterase Inhibitors in Alzheimer's Disease
por: Weng, Pei-Hsuan, et al.
Publicado: (2013)

Antagonist of Chrna1 prevents the pathogenesis of primary focal hyperhidrosis
por: Lin, Jian‐Bo, et al.
Publicado: (2022)

Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele
por: Oni, Eileen N., et al.
Publicado: (2016)

The Cumulative Effect of Gene–Gene Interactions Between GSTM1, CHRNA3, CHRNA5 and SOD3 Gene Polymorphisms Combined with Smoking on COPD Risk
por: Ganbold, Chimedlkhamsuren, et al.
Publicado: (2021)

The CHRNA5–A3–B4 Gene Cluster and Smoking: From Discovery to Therapeutics
por: Lassi, Glenda, et al.
Publicado: (2016)

Genetic influences on nicotinic α5 receptor (CHRNA5) CpG methylation and mRNA expression in brain and adipose tissue
por: Ramsay, Jessica E., et al.
Publicado: (2015)

Endogenous CHRNA7-ligand SLURP1 as a potential tumor suppressor and anti-nicotinic factor in pancreatic cancer
por: Throm, Verena M., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_rn4o8o5sbksboa554ddc19h9ti