Epigenetics in diagnosis of colorectal cancer

Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to di...

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Detalles Bibliográficos
Autores principales: Sameer, Aga Syed, Nissar, Saniya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shiraz University 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019333/
https://www.ncbi.nlm.nih.gov/pubmed/27844020
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author Sameer, Aga Syed
Nissar, Saniya
author_facet Sameer, Aga Syed
Nissar, Saniya
author_sort Sameer, Aga Syed
collection PubMed
description Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the early diagnosis of CRC. This will serve as the boon to the clinical management of the disease.
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spelling pubmed-50193332016-11-14 Epigenetics in diagnosis of colorectal cancer Sameer, Aga Syed Nissar, Saniya Mol Biol Res Commun Review Article Colorectal cancer (CRC) is a third most common epithelial carcinoma. CRC is known to develop from the early precancerous lesion to full blown malignancy via definite phases due to cumulative mutations and aberrant methylation of number of genes. The use of serum biomarkers that is non-invasive to discriminate cancer patients from healthy persons will prove to be an important tool to improve the early diagnosis of CRC. This will serve as the boon to the clinical management of the disease. Shiraz University 2016-03 /pmc/articles/PMC5019333/ /pubmed/27844020 Text en This is an Open Access article distributed under the terms of the Creative Commons Attribution License, (http://creativecommons.org/licenses/by/3.0/) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Sameer, Aga Syed
Nissar, Saniya
Epigenetics in diagnosis of colorectal cancer
title Epigenetics in diagnosis of colorectal cancer
title_full Epigenetics in diagnosis of colorectal cancer
title_fullStr Epigenetics in diagnosis of colorectal cancer
title_full_unstemmed Epigenetics in diagnosis of colorectal cancer
title_short Epigenetics in diagnosis of colorectal cancer
title_sort epigenetics in diagnosis of colorectal cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019333/
https://www.ncbi.nlm.nih.gov/pubmed/27844020
work_keys_str_mv AT sameeragasyed epigeneticsindiagnosisofcolorectalcancer
AT nissarsaniya epigeneticsindiagnosisofcolorectalcancer

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