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Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation

In the internal dose evaluation, the specific absorbed fraction (SAF) and S-value are calculated from the reference phantom based on Caucasian data. The differences in height and weight between Caucasian and Asian may lead to inaccurate dose estimation. In this study, we developed the Taiwanese refe...

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Autores principales: Chang, Shu-Jun, Hung, Shih-Yen, Liu, Yan-Lin, Jiang, Shiang-Huei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019459/
https://www.ncbi.nlm.nih.gov/pubmed/27618708
http://dx.doi.org/10.1371/journal.pone.0162359
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author Chang, Shu-Jun
Hung, Shih-Yen
Liu, Yan-Lin
Jiang, Shiang-Huei
author_facet Chang, Shu-Jun
Hung, Shih-Yen
Liu, Yan-Lin
Jiang, Shiang-Huei
author_sort Chang, Shu-Jun
collection PubMed
description In the internal dose evaluation, the specific absorbed fraction (SAF) and S-value are calculated from the reference phantom based on Caucasian data. The differences in height and weight between Caucasian and Asian may lead to inaccurate dose estimation. In this study, we developed the Taiwanese reference phantoms. 40 volunteers were recruited. Magnetic resonance images (MRI) were obtained, and the contours of 15 organs were drawn. The Taiwanese reference man (TRM) and Taiwanese reference woman (TRW) were constructed. For the SAF calculation, the differences in the self-absorption SAF (self-SAF) between the TRM, TRW, and Oak Ridge National Laboratory (ORNL) adult phantom were less than 10% when the difference in organ mass was less than 20%. The average SAF from liver to pancreas of TRM was 38% larger than that of the ORNL adult phantom, and the result of TRW was 2.02 times higher than that of the ORNL adult phantom. For the S-value calculation, the ratios of TRW and ORNL adult phantom ranged from 0.91 to 1.57, and the ratios of TRM and ORNL adult phantom ranged from 1.04 to 2.29. The SAF and S-value results were dominantly affected by the height, weight, organ mass, and geometric relationship between organs. By using the TRM and TRW, the accuracy of internal dose evaluation can be increased for radiation protection and nuclear medicine.
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spelling pubmed-50194592016-09-27 Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation Chang, Shu-Jun Hung, Shih-Yen Liu, Yan-Lin Jiang, Shiang-Huei PLoS One Research Article In the internal dose evaluation, the specific absorbed fraction (SAF) and S-value are calculated from the reference phantom based on Caucasian data. The differences in height and weight between Caucasian and Asian may lead to inaccurate dose estimation. In this study, we developed the Taiwanese reference phantoms. 40 volunteers were recruited. Magnetic resonance images (MRI) were obtained, and the contours of 15 organs were drawn. The Taiwanese reference man (TRM) and Taiwanese reference woman (TRW) were constructed. For the SAF calculation, the differences in the self-absorption SAF (self-SAF) between the TRM, TRW, and Oak Ridge National Laboratory (ORNL) adult phantom were less than 10% when the difference in organ mass was less than 20%. The average SAF from liver to pancreas of TRM was 38% larger than that of the ORNL adult phantom, and the result of TRW was 2.02 times higher than that of the ORNL adult phantom. For the S-value calculation, the ratios of TRW and ORNL adult phantom ranged from 0.91 to 1.57, and the ratios of TRM and ORNL adult phantom ranged from 1.04 to 2.29. The SAF and S-value results were dominantly affected by the height, weight, organ mass, and geometric relationship between organs. By using the TRM and TRW, the accuracy of internal dose evaluation can be increased for radiation protection and nuclear medicine. Public Library of Science 2016-09-12 /pmc/articles/PMC5019459/ /pubmed/27618708 http://dx.doi.org/10.1371/journal.pone.0162359 Text en © 2016 Chang et al http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Research Article
Chang, Shu-Jun
Hung, Shih-Yen
Liu, Yan-Lin
Jiang, Shiang-Huei
Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title_full Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title_fullStr Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title_full_unstemmed Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title_short Construction of Taiwanese Adult Reference Phantoms for Internal Dose Evaluation
title_sort construction of taiwanese adult reference phantoms for internal dose evaluation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019459/
https://www.ncbi.nlm.nih.gov/pubmed/27618708
http://dx.doi.org/10.1371/journal.pone.0162359
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