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Capturing a substrate in an activated RING E3/E2-SUMO complex

Post-translational protein modification by ubiquitin (Ub) and ubiquitin-like (Ubl) proteins such as small ubiquitin like modifier (SUMO) regulates processes including protein homeostasis, the DNA damage response, and the cell cycle. Proliferating cell nuclear antigen (PCNA) is modified by Ub or poly...

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Detalles Bibliográficos
Autores principales: Streich, Frederick C., Lima, Christopher D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5019495/
https://www.ncbi.nlm.nih.gov/pubmed/27509863
http://dx.doi.org/10.1038/nature19071