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Targeting Cannabinoid CB(2) Receptors in the Central Nervous System. Medicinal Chemistry Approaches with Focus on Neurodegenerative Disorders
Endocannabinoids activate two types of specific G-protein-coupled receptors (GPCRs), namely cannabinoid CB(1) and CB(2). Contrary to the psychotropic actions of agonists of CB(1) receptors, and serious side effects of the selective antagonists of this receptor, drugs acting on CB(2) receptors appear...
Autores principales: | Navarro, Gemma, Morales, Paula, Rodríguez-Cueto, Carmen, Fernández-Ruiz, Javier, Jagerovic, Nadine, Franco, Rafael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020102/ https://www.ncbi.nlm.nih.gov/pubmed/27679556 http://dx.doi.org/10.3389/fnins.2016.00406 |
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