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Sodium-Glucose Cotransporter-2 Inhibition and the Glomerulus: A Review
Blood glucose-lowering treatment options generally target insulin action or beta-cell function. In diabetes, expression of the sodium-glucose cotransporter-2 (SGLT2) genes is up-regulated and renal threshold increased, resulting in increased glucose reabsorption from glomerular filtrate, reducing ur...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Healthcare
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020120/ https://www.ncbi.nlm.nih.gov/pubmed/27423646 http://dx.doi.org/10.1007/s12325-016-0379-5 |