Cargando…

Preventing Paradoxical Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome in High-Risk Patients: Protocol of a Randomized Placebo-Controlled Trial of Prednisone (PredART Trial)

BACKGROUND: Early antiretroviral therapy (ART) initiation in patients diagnosed with HIV-associated tuberculosis (TB) reduces mortality among those with the lowest CD4 counts. At the same time, both early ART and a low CD4 count heighten the risk of paradoxical TB-associated immune reconstitution in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Stek, Cari, Schutz, Charlotte, Blumenthal, Lisette, Thienemann, Friedrich, Buyze, Jozefien, Nöstlinger, Christiana, Ravinetto, Raffaella, Wouters, Edwin, Colebunders, Robert, Maartens, Gary, Wilkinson, Robert J, Lynen, Lutgarde, Meintjes, Graeme
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	JMIR Publications 2016
Materias:	Protocol
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020311/ https://www.ncbi.nlm.nih.gov/pubmed/27571786 http://dx.doi.org/10.2196/resprot.6046

Ejemplares similares

Prednisone for the prevention of tuberculosis-associated IRIS (randomized controlled trial): Impact on the health-related quality of life
por: Wouters, Edwin, et al.
Publicado: (2022)

The effect of HIV-associated tuberculosis, tuberculosis-IRIS and prednisone on lung function
por: Stek, Cari, et al.
Publicado: (2020)

Diagnostic Accuracy of the INSHI Consensus Case Definition for the Diagnosis of Paradoxical Tuberculosis-IRIS
por: Stek, Cari, et al.
Publicado: (2021)

Relationship Between LTA4H Promotor Polymorphism and Tuberculosis-Associated Immune Reconstitution Inflammatory Syndrome and Its Prevention With Prednisone
por: Stek, Cari, et al.
Publicado: (2023)

The Immune Mechanisms of Lung Parenchymal Damage in Tuberculosis and the Role of Host-Directed Therapy
por: Stek, Cari, et al.
Publicado: (2018)

Comparison of predictive models for hepatitis C co-infection among HIV patients in Cambodia
por: Buyze, Jozefien, et al.
Publicado: (2020)

Factors influencing social self-disclosure among adolescents living with HIV in Eastern Africa
por: Nöstlinger, Christiana, et al.
Publicado: (2015)

HIV Prevalence by Race Co-Varies Closely with Concurrency and Number of Sex Partners in South Africa
por: Kenyon, Chris, et al.
Publicado: (2013)

Implementation and Operational Research: Computer-Assisted Intervention for Safer Sex in HIV-Positive Men Having Sex With Men: Findings of a European Randomized Multi-Center Trial
por: Nöstlinger, Christiana, et al.
Publicado: (2016)

Community-Based Active Tuberculosis Case Finding in Poor Urban Settlements of Phnom Penh, Cambodia: A Feasible and Effective Strategy
por: Lorent, Natalie, et al.
Publicado: (2014)

Development and external validation of a clinical prognostic score for death in visceral leishmaniasis patients in a high HIV co-infection burden area in Ethiopia
por: Abongomera, Charles, et al.
Publicado: (2017)

Daily and event‐driven pre‐exposure prophylaxis for men who have sex with men in Belgium: results of a prospective cohort measuring adherence, sexual behaviour and STI incidence
por: Vuylsteke, Bea, et al.
Publicado: (2019)

Female Genital Cutting and Hepatitis C Spread in Egypt
por: Kenyon, Chris, et al.
Publicado: (2013)

Development of a risk score to guide targeted hepatitis C testing among human immunodeficiency virus patients in Cambodia
por: De Weggheleire, Anja, et al.
Publicado: (2021)

Pre-Exposure Prophylaxis (PrEP) as an Additional Tool for HIV Prevention Among Men Who Have Sex With Men in Belgium: The Be-PrEP-ared Study Protocol
por: De Baetselier, Irith, et al.
Publicado: (2017)

Hepatitis C Prevalence and Validation of a Clinical Prediction Score for Targeted Screening among People Living with HIV in Ghana
por: Torpey, Kwasi, et al.
Publicado: (2021)

The tuberculosis-associated immune reconstitution inflammatory syndrome: recent advances in clinical and pathogenesis research
por: Walker, Naomi F., et al.
Publicado: (2018)

Increases in condomless chemsex associated with HIV acquisition in MSM but not heterosexuals attending a HIV testing center in Antwerp, Belgium
por: Kenyon, Chris, et al.
Publicado: (2018)

Study protocol of Prednisone in episodic Cluster Headache (PredCH): a randomized, double-blind, placebo-controlled parallel group trial to evaluate the efficacy and safety of oral prednisone as an add-on therapy in the prophylactic treatment of episodic cluster headache with verapamil
por: Holle, Dagny, et al.
Publicado: (2013)

Electrolyte and Metabolic Disturbances in Ebola Patients during a Clinical Trial, Guinea, 2015
por: van Griensven, Johan, et al.
Publicado: (2016)

Clinicopathologic and gastrointestinal effects of administration of prednisone, prednisone with omeprazole, or prednisone with probiotics to dogs: A double‐blind randomized trial
por: Rak, Mariola B., et al.
Publicado: (2023)

Patient-mix, programmatic characteristics, retention and predictors of attrition among patients starting antiretroviral therapy (ART) before and after the implementation of HIV “Treat All” in Zimbabwe
por: Makurumidze, Richard, et al.
Publicado: (2020)

Quality of Life in HIV Clinical Trials: Why Sexual Health Must Not Be Ignored
por: Koole, Olivier, et al.
Publicado: (2007)

Decrease of vitamin D concentration in patients with HIV infection on a non nucleoside reverse transcriptase inhibitor-containing regimen
por: Conesa-Botella, Anali, et al.
Publicado: (2010)

Plasma Pharmacokinetics of High-Dose Oral versus Intravenous Rifampicin in Patients with Tuberculous Meningitis: a Randomized Controlled Trial
por: Wasserman, Sean, et al.
Publicado: (2021)

WWW internet vznikl před dvaceti roky. A nebo před osmnácti?
Publicado: (2009)

Measuring Health-Related Quality of Life of HIV-Positive Adolescents in Resource-Constrained Settings
por: Masquillier, Caroline, et al.
Publicado: (2012)

PReS-FINAL-2184: A randomized trial in new onset juvenile dermatomyositis: prednisone versus prednisone plus cyclosporine versus prednisone plus methotrexate
por: Ruperto, N, et al.
Publicado: (2013)

Antimicrobial Consumption and Susceptibility of Neisseria gonorrhoeae: A Global Ecological Analysis
por: Kenyon, Chris, et al.
Publicado: (2018)

Predictors of condom use and refusal among the population of Free State province in South Africa
por: Chandran, Thoovakkunon Moorkoth, et al.
Publicado: (2012)

SuperPred: drug classification and target prediction
por: Dunkel, Mathias, et al.
Publicado: (2008)

A cross-sectional study of hepatitis C among people living with HIV in Cambodia: Prevalence, risk factors, and potential for targeted screening
por: De Weggheleire, Anja, et al.
Publicado: (2017)

The Prevalence of HIV by Ethnic Group Is Correlated with HSV-2 and Syphilis Prevalence in Kenya, South Africa, the United Kingdom, and the United States
por: Kenyon, Chris Richard, et al.
Publicado: (2014)

Strong association between higher-risk sex and HIV prevalence at the regional level: an ecological study of 27 sub-Saharan African countries
por: Kenyon, Chris R., et al.
Publicado: (2018)

Clinical trial protocol: PRednisolone in early diffuse cutaneous Systemic Sclerosis (PRedSS)
por: Herrick, Ariane L, et al.
Publicado: (2020)

From Physical Distancing to Social Loneliness among Gay Men and Other Men Having Sex with Men in Belgium: Examining the Disruption of the Social Network and Social Support Structures
por: Thunnissen, Estrelle, et al.
Publicado: (2022)

Standard versus double dose dolutegravir in patients with HIV-associated tuberculosis: a phase 2 non-comparative randomised controlled (RADIANT-TB) trial
por: Griesel, Rulan, et al.
Publicado: (2021)

Use of Pentamidine As Secondary Prophylaxis to Prevent Visceral Leishmaniasis Relapse in HIV Infected Patients, the First Twelve Months of a Prospective Cohort Study
por: Diro, Ermias, et al.
Publicado: (2015)

SuperPred: update on drug classification and target prediction
por: Nickel, Janette, et al.
Publicado: (2014)

Design and analysis considerations in the Ebola_Tx trial evaluating convalescent plasma in the treatment of Ebola virus disease in Guinea during the 2014–2015 outbreak
por: Edwards, Tansy, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_dm43gkhgb80iki3g7m7akeg4r5