Cargando…
The legacy of the F344 rat as a cancer bioassay model (a retrospective summary of three common F344 rat neoplasms)
The Fischer 344 (F344) rat was used by the National Toxicology Program (NTP) for over 5 decades for toxicity and carcinogenicity studies. However, in 2006, the NTP decided to switch to a different rat stock due largely to high background control incidences of Leydig cell tumors (LCTs) and mononuclea...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020328/ https://www.ncbi.nlm.nih.gov/pubmed/27278595 http://dx.doi.org/10.1080/10408444.2016.1174669 |