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Predicting lung dosimetry of inhaled particleborne benzo[a]pyrene using physiologically based pharmacokinetic modeling

Benzo[a]pyrene (BaP) is a by-product of incomplete combustion of fossil fuels and plant/wood products, including tobacco. A physiologically based pharmacokinetic (PBPK) model for BaP for the rat was extended to simulate inhalation exposures to BaP in rats and humans including particle deposition and...

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Detalles Bibliográficos
Autores principales:	Campbell, Jerry, Franzen, Allison, Van Landingham, Cynthia, Lumpkin, Michael, Crowell, Susan, Meredith, Clive, Loccisano, Anne, Gentry, Robinan, Clewell, Harvey
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Taylor & Francis 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020340/ https://www.ncbi.nlm.nih.gov/pubmed/27569524 http://dx.doi.org/10.1080/08958378.2016.1214768

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