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The association between phosphatase and tensin homolog hypermethylation and patients with breast cancer, a meta-analysis and literature review
The Phosphatase and tensin homolog (PTEN) protein is a negative regulator of the Akt pathway, leading to suppression of apoptois and increased cell survival. Its role as a tumor-suppressor gene has been adequately substantiated, and PTEN hypermethylation has been demonstrated in familial and sporadi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Nature Publishing Group
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020353/ https://www.ncbi.nlm.nih.gov/pubmed/27620353 http://dx.doi.org/10.1038/srep32723 |