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Molecular organization, localization and orientation of antifungal antibiotic amphotericin B in a single lipid bilayer
Amphotericin B is a popular antifungal antibiotic, a gold standard in treatment of systemic mycotic infections, due to its high effectiveness. On the other hand, applicability of the drug is limited by its considerable toxicity to patients. Biomembranes are a primary target of physiological activity...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020354/ https://www.ncbi.nlm.nih.gov/pubmed/27620838 http://dx.doi.org/10.1038/srep32780 |