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Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine

BACKGROUND: There has been some evidence to suggest that the addition of chloroquine (CQ) or quinine (QN) to 8-aminoquinoline (8-AQ) treatment regimens may increase the therapeutic efficacy of the 8-AQ and simultaneously mitigate against its haemolytic toxicity. However, both CQ and QN are considere...

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Detalles Bibliográficos
Autores principales:	Fasinu, Pius S., Tekwani, Babu L., Avula, Bharathi, Chaurasiya, Narayan D., Nanayakkara, N. P. Dhammika, Wang, Yan-Hong, Khan, Ikhlas A., Walker, Larry A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2016
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020452/ https://www.ncbi.nlm.nih.gov/pubmed/27618912 http://dx.doi.org/10.1186/s12936-016-1509-x

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