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A phase-I trial of pre‐operative, margin intensive, stereotactic body radiation therapy for pancreatic cancer: the ‘SPARC’ trial protocol

BACKGROUND: Standard therapy for borderline-resectable pancreatic cancer in the UK is surgery with adjuvant chemotherapy, but rates of resection with clear margins are unsatisfactory and overall survival remains poor. Meta-analysis of single-arm studies shows the potential of neo-adjuvant chemo-radi...

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Detalles Bibliográficos
Autores principales: Holyoake, Daniel L. P., Ward, Elizabeth, Grose, Derek, McIntosh, David, Sebag-Montefiore, David, Radhakrishna, Ganesh, Patel, Neel, Silva, Michael, Mukherjee, Somnath, Strauss, Victoria Y., Odondi, Lang’o, Fokas, Emmanouil, Melcher, Alan, Hawkins, Maria A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020462/
https://www.ncbi.nlm.nih.gov/pubmed/27619800
http://dx.doi.org/10.1186/s12885-016-2765-4