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Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not s...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020493/ https://www.ncbi.nlm.nih.gov/pubmed/27620282 http://dx.doi.org/10.1038/srep33069 |
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author | Zhao, Mengfei Yue, Zhendong Zhao, Hongwei Wang, Lei Fan, Zhenhua He, Fuliang Yao, Jiannan Dong, Xiaoqun Liu, Fuquan |
author_facet | Zhao, Mengfei Yue, Zhendong Zhao, Hongwei Wang, Lei Fan, Zhenhua He, Fuliang Yao, Jiannan Dong, Xiaoqun Liu, Fuquan |
author_sort | Zhao, Mengfei |
collection | PubMed |
description | The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not specific and the relationship between different types of PVT and technical success rate of TIPS is unclear. What’s more, we aimed to explore the relationship between survival and vascular patency immediately after TIPS. 191 subjects underwent retrospective assessment. Appropriate TIPS procedures were performed based on our more specific classification. The overall success rate of TIPS was 95.8% (183/191). Success rate was significantly different between Grade II and Grade IV thrombosis (χ(2) = 5.294, P = 0.021). The 1-, 2-, 3-, 4-and 5-year survival rates were 95.6%, 89.1%, 83.1%, 76.5% and 67.8%, respectively. The overall survival time of completely patent PV and incomplete patent PV immediately after TIPS was 57.05 ± 0.75 vs. 39.12 ± 2.64 months, respectively (P < 0.0001). We conclude that appropriate TIPS procedures and lower grade of PVT are essential for better technical success rate of TIPS. The patency of target vessels is important for survival. |
format | Online Article Text |
id | pubmed-5020493 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Nature Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-50204932016-09-20 Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis Zhao, Mengfei Yue, Zhendong Zhao, Hongwei Wang, Lei Fan, Zhenhua He, Fuliang Yao, Jiannan Dong, Xiaoqun Liu, Fuquan Sci Rep Article The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not specific and the relationship between different types of PVT and technical success rate of TIPS is unclear. What’s more, we aimed to explore the relationship between survival and vascular patency immediately after TIPS. 191 subjects underwent retrospective assessment. Appropriate TIPS procedures were performed based on our more specific classification. The overall success rate of TIPS was 95.8% (183/191). Success rate was significantly different between Grade II and Grade IV thrombosis (χ(2) = 5.294, P = 0.021). The 1-, 2-, 3-, 4-and 5-year survival rates were 95.6%, 89.1%, 83.1%, 76.5% and 67.8%, respectively. The overall survival time of completely patent PV and incomplete patent PV immediately after TIPS was 57.05 ± 0.75 vs. 39.12 ± 2.64 months, respectively (P < 0.0001). We conclude that appropriate TIPS procedures and lower grade of PVT are essential for better technical success rate of TIPS. The patency of target vessels is important for survival. Nature Publishing Group 2016-09-13 /pmc/articles/PMC5020493/ /pubmed/27620282 http://dx.doi.org/10.1038/srep33069 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ |
spellingShingle | Article Zhao, Mengfei Yue, Zhendong Zhao, Hongwei Wang, Lei Fan, Zhenhua He, Fuliang Yao, Jiannan Dong, Xiaoqun Liu, Fuquan Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title | Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title_full | Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title_fullStr | Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title_full_unstemmed | Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title_short | Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
title_sort | techniques of tips in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020493/ https://www.ncbi.nlm.nih.gov/pubmed/27620282 http://dx.doi.org/10.1038/srep33069 |
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