Cargando…

Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis

The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not s...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Mengfei, Yue, Zhendong, Zhao, Hongwei, Wang, Lei, Fan, Zhenhua, He, Fuliang, Yao, Jiannan, Dong, Xiaoqun, Liu, Fuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020493/
https://www.ncbi.nlm.nih.gov/pubmed/27620282
http://dx.doi.org/10.1038/srep33069
_version_ 1782453213496082432
author Zhao, Mengfei
Yue, Zhendong
Zhao, Hongwei
Wang, Lei
Fan, Zhenhua
He, Fuliang
Yao, Jiannan
Dong, Xiaoqun
Liu, Fuquan
author_facet Zhao, Mengfei
Yue, Zhendong
Zhao, Hongwei
Wang, Lei
Fan, Zhenhua
He, Fuliang
Yao, Jiannan
Dong, Xiaoqun
Liu, Fuquan
author_sort Zhao, Mengfei
collection PubMed
description The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not specific and the relationship between different types of PVT and technical success rate of TIPS is unclear. What’s more, we aimed to explore the relationship between survival and vascular patency immediately after TIPS. 191 subjects underwent retrospective assessment. Appropriate TIPS procedures were performed based on our more specific classification. The overall success rate of TIPS was 95.8% (183/191). Success rate was significantly different between Grade II and Grade IV thrombosis (χ(2) = 5.294, P = 0.021). The 1-, 2-, 3-, 4-and 5-year survival rates were 95.6%, 89.1%, 83.1%, 76.5% and 67.8%, respectively. The overall survival time of completely patent PV and incomplete patent PV immediately after TIPS was 57.05 ± 0.75 vs. 39.12 ± 2.64 months, respectively (P < 0.0001). We conclude that appropriate TIPS procedures and lower grade of PVT are essential for better technical success rate of TIPS. The patency of target vessels is important for survival.
format Online
Article
Text
id pubmed-5020493
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Nature Publishing Group
record_format MEDLINE/PubMed
spelling pubmed-50204932016-09-20 Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis Zhao, Mengfei Yue, Zhendong Zhao, Hongwei Wang, Lei Fan, Zhenhua He, Fuliang Yao, Jiannan Dong, Xiaoqun Liu, Fuquan Sci Rep Article The patients of liver cirrhosis associated with portal vein thrombosis (PVT) can be effectively treated by transjugular intrahepatic portosystemic stent shunt (TIPS). Although the corresponding TIPS procedures have already performed on the patients to different types of PVT, the procedures are not specific and the relationship between different types of PVT and technical success rate of TIPS is unclear. What’s more, we aimed to explore the relationship between survival and vascular patency immediately after TIPS. 191 subjects underwent retrospective assessment. Appropriate TIPS procedures were performed based on our more specific classification. The overall success rate of TIPS was 95.8% (183/191). Success rate was significantly different between Grade II and Grade IV thrombosis (χ(2) = 5.294, P = 0.021). The 1-, 2-, 3-, 4-and 5-year survival rates were 95.6%, 89.1%, 83.1%, 76.5% and 67.8%, respectively. The overall survival time of completely patent PV and incomplete patent PV immediately after TIPS was 57.05 ± 0.75 vs. 39.12 ± 2.64 months, respectively (P < 0.0001). We conclude that appropriate TIPS procedures and lower grade of PVT are essential for better technical success rate of TIPS. The patency of target vessels is important for survival. Nature Publishing Group 2016-09-13 /pmc/articles/PMC5020493/ /pubmed/27620282 http://dx.doi.org/10.1038/srep33069 Text en Copyright © 2016, The Author(s) http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Zhao, Mengfei
Yue, Zhendong
Zhao, Hongwei
Wang, Lei
Fan, Zhenhua
He, Fuliang
Yao, Jiannan
Dong, Xiaoqun
Liu, Fuquan
Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title_full Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title_fullStr Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title_full_unstemmed Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title_short Techniques of TIPS in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
title_sort techniques of tips in the treatment of liver cirrhosis combined with incompletely occlusive main portal vein thrombosis
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020493/
https://www.ncbi.nlm.nih.gov/pubmed/27620282
http://dx.doi.org/10.1038/srep33069
work_keys_str_mv AT zhaomengfei techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT yuezhendong techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT zhaohongwei techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT wanglei techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT fanzhenhua techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT hefuliang techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT yaojiannan techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT dongxiaoqun techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis
AT liufuquan techniquesoftipsinthetreatmentoflivercirrhosiscombinedwithincompletelyocclusivemainportalveinthrombosis