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Chondroprotective effect of high-molecular-weight hyaluronic acid on osteoarthritic chondrocytes in a co-cultivation inflammation model with M1 macrophages
BACKGROUND: Osteoarthritis (OA) is described by an imbalance between anabolic and catabolic processes in the affected joint. This dysregulation of metabolism affects not only chondrocytes within cartilage tissue but also the cells of the synovial membrane across the border of the joint. An important...
Autores principales: | Bauer, Christoph, Niculescu-Morzsa, Eugenia, Jeyakumar, Vivek, Kern, Daniela, Späth, Stephan S., Nehrer, Stefan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020517/ https://www.ncbi.nlm.nih.gov/pubmed/27625590 http://dx.doi.org/10.1186/s12950-016-0139-y |
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