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Advanced glycation end products impair the functions of saphenous vein but not thoracic artery smooth muscle cells through RAGE/MAPK signalling pathway in diabetes

Saphenous vein (SV) and internal thoracic artery (ITA) are commonly used bypass conduits. However, graft failure occurs in SV rather than in ITA, especially in diabetes (DM). The mechanism for this difference has not been fully understood. Accumulation of advanced glycation end products (AGEs) and a...

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Detalles Bibliográficos
Autores principales: Sun, Yongxin, Kang, Le, Li, Jun, Liu, Huan, Wang, Yulin, Wang, Chunsheng, Zou, Yunzeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020631/
https://www.ncbi.nlm.nih.gov/pubmed/27297874
http://dx.doi.org/10.1111/jcmm.12886