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Genetic polymorphism of the Nrf2 promoter region is associated with vitiligo risk in Han Chinese populations

The nuclear factor erythroid‐derived two‐like 2‐antioxidant response element (Nrf2‐ARE) pathway and its downstream antioxidant enzyme heme oxygenase‐1 (HMOX1 or HO‐1) play essential roles in H(2)O(2)‐induced oxidative damage in human melanocytes. However, the link between Nrf2 promoter polymorphisms...

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Detalles Bibliográficos
Autores principales: Song, Pu, Li, Kai, Liu, Ling, Wang, Xiaowen, Jian, Zhe, Zhang, Weigang, Wang, Gang, Li, Chunying, Gao, Tianwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020638/
https://www.ncbi.nlm.nih.gov/pubmed/27222475
http://dx.doi.org/10.1111/jcmm.12874