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Changes in intracellular copper concentration and copper-regulating gene expression after PC12 differentiation into neurons

It is suspected that some neurodegenerative diseases are a result of the disturbance of copper (Cu) homeostasis, although it remains unclear whether the disturbance of Cu homeostasis has aberrant effects on neurons. Herein, we investigated Cu metabolism specifically in neurons in terms of changes in...

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Detalles Bibliográficos
Autores principales: Ogra, Yasumitsu, Tejima, Aya, Hatakeyama, Naohiro, Shiraiwa, Moeko, Wu, Siyuan, Ishikawa, Tsutomu, Yawata, Ayako, Anan, Yasumi, Suzuki, Noriyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020689/
https://www.ncbi.nlm.nih.gov/pubmed/27623342
http://dx.doi.org/10.1038/srep33007