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Changes in intracellular copper concentration and copper-regulating gene expression after PC12 differentiation into neurons
It is suspected that some neurodegenerative diseases are a result of the disturbance of copper (Cu) homeostasis, although it remains unclear whether the disturbance of Cu homeostasis has aberrant effects on neurons. Herein, we investigated Cu metabolism specifically in neurons in terms of changes in...
Autores principales: | Ogra, Yasumitsu, Tejima, Aya, Hatakeyama, Naohiro, Shiraiwa, Moeko, Wu, Siyuan, Ishikawa, Tsutomu, Yawata, Ayako, Anan, Yasumi, Suzuki, Noriyuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020689/ https://www.ncbi.nlm.nih.gov/pubmed/27623342 http://dx.doi.org/10.1038/srep33007 |
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