Cargando…

Sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the CPRD primary care database

INTRODUCTION: Voltage-gated sodium channel (VGSC)-inhibiting drugs are commonly used to treat epilepsy and cardiac arrhythmia. VGSCs are also widely expressed in various cancers, including those of the breast, bowel and prostate. A number of VGSC-inhibiting drugs have been shown to inhibit cancer ce...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fairhurst, Caroline, Martin, Fabiola, Watt, Ian, Doran, Tim, Bland, Martin, Brackenbury, William J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2016
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020752/ https://www.ncbi.nlm.nih.gov/pubmed/27601493 http://dx.doi.org/10.1136/bmjopen-2016-011661

Ejemplares similares

Exposure to sodium channel-inhibiting drugs and cancer survival: protocol for a cohort study using the QResearch primary care database
por: Fairhurst, Caroline, et al.
Publicado: (2014)

Sodium channel-inhibiting drugs and cancer-specific survival: a population-based study of electronic primary care data
por: Fairhurst, Caroline, et al.
Publicado: (2023)

Sodium channel-inhibiting drugs and survival of breast, colon and prostate cancer: a population-based study
por: Fairhurst, Caroline, et al.
Publicado: (2015)

Therapeutic Value of Voltage-Gated Sodium Channel Inhibitors in Breast, Colorectal, and Prostate Cancer: A Systematic Review
por: Martin, Fabiola, et al.
Publicado: (2015)

Comparison of antibiotic prescribing records in two UK primary care electronic health record systems: cohort study using CPRD GOLD and CPRD Aurum databases
por: Gulliford, Martin C, et al.
Publicado: (2020)

Blocking channels to metastasis: targeting sodium transport in breast cancer
por: Brackenbury, William J., et al.
Publicado: (2023)

Obesity and healthcare resource utilization: results from Clinical Practice Research Database (CPRD)
por: le Roux, C. W., et al.
Publicado: (2018)

Validation of asthma recording in the Clinical Practice Research Datalink (CPRD)
por: Nissen, Francis, et al.
Publicado: (2017)

Exposure to combined oral contraceptives and risk of venous thromboembolism: a protocol for nested case–control studies using the QResearch and the CPRD databases
por: Vinogradova, Yana, et al.
Publicado: (2014)

Use of menopausal hormone therapy and risk of dementia: nested case-control studies using QResearch and CPRD databases
por: Vinogradova, Yana, et al.
Publicado: (2021)

In Vivo Evidence for Voltage-Gated Sodium Channel Expression in Carcinomas and Potentiation of Metastasis
por: Djamgoz, Mustafa B. A., et al.
Publicado: (2019)

Pharmacological and nutritional targeting of voltage-gated sodium channels in the treatment of cancers
por: Lopez-Charcas, Osbaldo, et al.
Publicado: (2021)

Calcium channel blockers and cancer: a risk analysis using the UK Clinical Practice Research Datalink (CPRD)
por: Grimaldi-Bensouda, Lamiae, et al.
Publicado: (2016)

The Emerging Role of Voltage-Gated Sodium Channels in Tumor Biology
por: Mao, Weijia, et al.
Publicado: (2019)

Use of combined oral contraceptives and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases
por: Vinogradova, Yana, et al.
Publicado: (2015)

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases
por: Vinogradova, Yana, et al.
Publicado: (2019)

Use of hormone replacement therapy and risk of venous thromboembolism: nested case-control studies using the QResearch and CPRD databases
Publicado: (2019)

Use of hormone replacement therapy and risk of breast cancer: nested case-control studies using the QResearch and CPRD databases
por: Vinogradova, Yana, et al.
Publicado: (2020)

Data Resource Profile: Clinical Practice Research Datalink (CPRD)
por: Herrett, Emily, et al.
Publicado: (2015)

Quality of recording of diabetes in the UK: how does the GP's method of coding clinical data affect incidence estimates? Cross-sectional study using the CPRD database
por: Tate, A Rosemary, et al.
Publicado: (2017)

Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database
por: Kostikas, Konstantinos, et al.
Publicado: (2020)

Evaluating the Performance of High-Dimensional Propensity Scores Compared with Standard Propensity Scores for Comparing Antihypertensive Therapies in the CPRD GOLD Database
por: Simon, Virginie, et al.
Publicado: (2023)

Use of oral anticoagulants in older people with atrial fibrillation in UK general practice: protocol for a cohort study using the Clinical Practice Research Datalink (CPRD) database
por: Mitchell, Anneka, et al.
Publicado: (2019)

The sodium channel-blocking antiepileptic drug phenytoin inhibits breast tumour growth and metastasis
por: Nelson, Michaela, et al.
Publicado: (2015)

Data resource profile: Clinical Practice Research Datalink (CPRD) Aurum
por: Wolf, Achim, et al.
Publicado: (2019)

Encounters for foot and ankle pain in UK primary care: a population-based cohort study of CPRD data
por: Ferguson, Rachel, et al.
Publicado: (2019)

Clinical Impact and Healthcare Resource Utilization Associated with Early versus Late COPD Diagnosis in Patients from UK CPRD Database [Corrigendum]
Publicado: (2020)

Severe mental illnesses and mortality following COVID-19 infection: Data linkage study using the Clinical Practice Research Database (CPRD).
por: Das-Munshi, Jayati, et al.
Publicado: (2022)

Blockade of voltage-gated sodium channels inhibits invasion of endocrine-resistant breast cancer cells
por: MOHAMMED, FATIMA H., et al.
Publicado: (2015)

Development and validation of a nomogram to predict overall survival and cancer-specific survival in patients with primary intracranial malignant lymphoma: A Retrospective study based on the SEER database
por: Yang, Ziyue, et al.
Publicado: (2023)

Investigating the optimal handling of uncertain pregnancy episodes in the CPRD GOLD Pregnancy Register: a methodological study using UK primary care data
por: Campbell, Jennifer, et al.
Publicado: (2022)

Representativeness and optimal use of body mass index (BMI) in the UK Clinical Practice Research Datalink (CPRD)
por: Bhaskaran, Krishnan, et al.
Publicado: (2013)

Survival Analysis and Prediction Model of ASCP Based on SEER Database
por: Lv, Sun-Yuan, et al.
Publicado: (2022)

Cost-effectiveness of antibiotics for COPD management: observational analysis using CPRD data
por: Ronaldson, Sarah J., et al.
Publicado: (2017)

Implications of lower risk thresholds for statin treatment in primary prevention: Analysis of CPRD and simulation modelling of annual cholesterol monitoring
por: McFadden, Emily, et al.
Publicado: (2015)

2647. Influenza Treatment Rates in UK Primary Care Settings: Real-World Data Analysis of the CPRD, 2003–2018
por: Chawla, Devika, et al.
Publicado: (2019)

DDESC: Dragon database for exploration of sodium channels in human
por: Sagar, Sunil, et al.
Publicado: (2008)

Na(+) Channel β Subunits: Overachievers of the Ion Channel Family
por: Brackenbury, William J., et al.
Publicado: (2011)

The sodium channel β1 subunit mediates outgrowth of neurite-like processes on breast cancer cells and promotes tumour growth and metastasis
por: Nelson, Michaela, et al.
Publicado: (2014)

Epidemiology and current treatment patterns of treatment-resistant depression in Scotland: a CPRD study
por: Ming, Timothy, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_aonj21e1ebn33ot0cn75l5l905