Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis

Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a type of severe adverse cutaneous drug reaction characterized by fever, skin eruption, hematological abnormalities, and internal organ involvement. Although anticonvulsant drugs are mainly implicated in DRESS, newer anticonvulsan...

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Autores principales: Saha, Mahimanjan, Gorai, Surajit, Madhab, Vaswatee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020775/
https://www.ncbi.nlm.nih.gov/pubmed/27651712
http://dx.doi.org/10.4103/0976-500X.189681
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author Saha, Mahimanjan
Gorai, Surajit
Madhab, Vaswatee
author_facet Saha, Mahimanjan
Gorai, Surajit
Madhab, Vaswatee
author_sort Saha, Mahimanjan
collection PubMed
description Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a type of severe adverse cutaneous drug reaction characterized by fever, skin eruption, hematological abnormalities, and internal organ involvement. Although anticonvulsant drugs are mainly implicated in DRESS, newer anticonvulsants such as oxcarbazepine-induced definite cases of DRESS syndrome are rare and oxcarbazepine-induced DRESS syndrome presenting as exfoliative dermatitis is even rarer. We report a case of a 35-year-old male who developed DRESS syndrome presenting as exfoliative dermatitis after taking oxcarbazepine for 3 weeks.
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spelling pubmed-50207752016-09-20 Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis Saha, Mahimanjan Gorai, Surajit Madhab, Vaswatee J Pharmacol Pharmacother Case Report Drug rash with eosinophilia and systemic symptoms (DRESS) syndrome is a type of severe adverse cutaneous drug reaction characterized by fever, skin eruption, hematological abnormalities, and internal organ involvement. Although anticonvulsant drugs are mainly implicated in DRESS, newer anticonvulsants such as oxcarbazepine-induced definite cases of DRESS syndrome are rare and oxcarbazepine-induced DRESS syndrome presenting as exfoliative dermatitis is even rarer. We report a case of a 35-year-old male who developed DRESS syndrome presenting as exfoliative dermatitis after taking oxcarbazepine for 3 weeks. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC5020775/ /pubmed/27651712 http://dx.doi.org/10.4103/0976-500X.189681 Text en Copyright: © Journal of Pharmacology and Pharmacotherapeutics http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Saha, Mahimanjan
Gorai, Surajit
Madhab, Vaswatee
Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title_full Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title_fullStr Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title_full_unstemmed Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title_short Oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
title_sort oxcarbazepine-induced drug rash with eosinophilia and systemic symptoms syndrome presenting as exfoliative dermatitis
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020775/
https://www.ncbi.nlm.nih.gov/pubmed/27651712
http://dx.doi.org/10.4103/0976-500X.189681
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AT madhabvaswatee oxcarbazepineinduceddrugrashwitheosinophiliaandsystemicsymptomssyndromepresentingasexfoliativedermatitis

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