Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT

Radiation-induced sarcomas (RIS) or postirradiation sarcomas have been reported as a rare long-term complication of radiation therapy (RT). The survival benefit offered by radiotherapy has been masked by an increase in the incidence of these sarcomas, thus making radiotherapy a double-edged sword. R...

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Autores principales: Siraj, Fouzia, Dalal, Varsha, Kaur, Manveen, Suri, Kapil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020799/
https://www.ncbi.nlm.nih.gov/pubmed/27651746
http://dx.doi.org/10.4103/1450-1147.172306
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author Siraj, Fouzia
Dalal, Varsha
Kaur, Manveen
Suri, Kapil
author_facet Siraj, Fouzia
Dalal, Varsha
Kaur, Manveen
Suri, Kapil
author_sort Siraj, Fouzia
collection PubMed
description Radiation-induced sarcomas (RIS) or postirradiation sarcomas have been reported as a rare long-term complication of radiation therapy (RT). The survival benefit offered by radiotherapy has been masked by an increase in the incidence of these sarcomas, thus making radiotherapy a double-edged sword. RIS generally develop with a mean latency period of 10-15 years and encompass different histological types. We report a case of oral leiomyosarcoma with a rather short latency period of 4 years after the radiotherapy of the prior oral squamous cell carcinoma (OSCC) detected on fluorine-18 (18F)-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT). The rarity of occurrence of leiomyosarcoma in the oral cavity is also highlighted.
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spelling pubmed-50207992016-09-20 Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT Siraj, Fouzia Dalal, Varsha Kaur, Manveen Suri, Kapil World J Nucl Med Case Report Radiation-induced sarcomas (RIS) or postirradiation sarcomas have been reported as a rare long-term complication of radiation therapy (RT). The survival benefit offered by radiotherapy has been masked by an increase in the incidence of these sarcomas, thus making radiotherapy a double-edged sword. RIS generally develop with a mean latency period of 10-15 years and encompass different histological types. We report a case of oral leiomyosarcoma with a rather short latency period of 4 years after the radiotherapy of the prior oral squamous cell carcinoma (OSCC) detected on fluorine-18 (18F)-fluoro-2-deoxy-D-glucose (FDG) positron emission tomography/computed tomography (PET/CT). The rarity of occurrence of leiomyosarcoma in the oral cavity is also highlighted. Medknow Publications & Media Pvt Ltd 2016-09 /pmc/articles/PMC5020799/ /pubmed/27651746 http://dx.doi.org/10.4103/1450-1147.172306 Text en Copyright: © World Journal of Nuclear Medicine http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Siraj, Fouzia
Dalal, Varsha
Kaur, Manveen
Suri, Kapil
Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title_full Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title_fullStr Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title_full_unstemmed Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title_short Radiation-induced Leiomyosarcoma of the Oral Cavity: A Rare Occurrence Detected on 18F-FDG PET/CT
title_sort radiation-induced leiomyosarcoma of the oral cavity: a rare occurrence detected on 18f-fdg pet/ct
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020799/
https://www.ncbi.nlm.nih.gov/pubmed/27651746
http://dx.doi.org/10.4103/1450-1147.172306
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AT kaurmanveen radiationinducedleiomyosarcomaoftheoralcavityarareoccurrencedetectedon18ffdgpetct
AT surikapil radiationinducedleiomyosarcomaoftheoralcavityarareoccurrencedetectedon18ffdgpetct

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