Cargando…

Protective mechanisms of microRNA-27a against oxygen-glucose deprivation-induced injuries in hippocampal neurons

Hypoxic injuries during fetal distress have been shown to cause reduced expression of microRNA-27a (miR-27a), which regulates sensitivity of cortical neurons to apoptosis. We hypothesized that miR-27a overexpression attenuates hypoxia- and ischemia-induced neuronal apoptosis by regulating FOXO1, an...

Descripción completa

Detalles Bibliográficos
Autores principales: Cai, Qun, Wang, Ting, Yang, Wen-jie, Fen, Xing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020828/
https://www.ncbi.nlm.nih.gov/pubmed/27651777
http://dx.doi.org/10.4103/1673-5374.189194