Cargando…

Rebuilding motor function of the spinal cord based on functional electrical stimulation

Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience. The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology. In this study, the locations of motor funct...

Descripción completa

Detalles Bibliográficos
Autores principales: Shen, Xiao-yan, Du, Wei, Huang, Wei, Chen, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020833/
https://www.ncbi.nlm.nih.gov/pubmed/27651782
http://dx.doi.org/10.4103/1673-5374.189199
_version_ 1782453275663007744
author Shen, Xiao-yan
Du, Wei
Huang, Wei
Chen, Yi
author_facet Shen, Xiao-yan
Du, Wei
Huang, Wei
Chen, Yi
author_sort Shen, Xiao-yan
collection PubMed
description Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience. The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology. In this study, the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology. A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn. Based on the individual experimental parameters and normalized coordinates of the motor function sites, the motor function sites that control a certain muscle were calculated. Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension, hip flexion, ankle plantarflexion, and ankle dorsiflexion movements were successfully achieved. The results show that the map of the spinal cord motor function sites was valid. This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury.
format Online
Article
Text
id pubmed-5020833
institution National Center for Biotechnology Information
language English
publishDate 2016
publisher Medknow Publications & Media Pvt Ltd
record_format MEDLINE/PubMed
spelling pubmed-50208332016-09-20 Rebuilding motor function of the spinal cord based on functional electrical stimulation Shen, Xiao-yan Du, Wei Huang, Wei Chen, Yi Neural Regen Res Research Article Rebuilding the damaged motor function caused by spinal cord injury is one of the most serious challenges in clinical neuroscience. The function of the neural pathway under the damaged sites can be rebuilt using functional electrical stimulation technology. In this study, the locations of motor function sites in the lumbosacral spinal cord were determined with functional electrical stimulation technology. A three-dimensional map of the lumbosacral spinal cord comprising the relationship between the motor function sites and the corresponding muscle was drawn. Based on the individual experimental parameters and normalized coordinates of the motor function sites, the motor function sites that control a certain muscle were calculated. Phasing pulse sequences were delivered to the determined motor function sites in the spinal cord and hip extension, hip flexion, ankle plantarflexion, and ankle dorsiflexion movements were successfully achieved. The results show that the map of the spinal cord motor function sites was valid. This map can provide guidance for the selection of electrical stimulation sites during the rebuilding of motor function after spinal cord injury. Medknow Publications & Media Pvt Ltd 2016-08 /pmc/articles/PMC5020833/ /pubmed/27651782 http://dx.doi.org/10.4103/1673-5374.189199 Text en Copyright: © Neural Regeneration Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Research Article
Shen, Xiao-yan
Du, Wei
Huang, Wei
Chen, Yi
Rebuilding motor function of the spinal cord based on functional electrical stimulation
title Rebuilding motor function of the spinal cord based on functional electrical stimulation
title_full Rebuilding motor function of the spinal cord based on functional electrical stimulation
title_fullStr Rebuilding motor function of the spinal cord based on functional electrical stimulation
title_full_unstemmed Rebuilding motor function of the spinal cord based on functional electrical stimulation
title_short Rebuilding motor function of the spinal cord based on functional electrical stimulation
title_sort rebuilding motor function of the spinal cord based on functional electrical stimulation
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5020833/
https://www.ncbi.nlm.nih.gov/pubmed/27651782
http://dx.doi.org/10.4103/1673-5374.189199
work_keys_str_mv AT shenxiaoyan rebuildingmotorfunctionofthespinalcordbasedonfunctionalelectricalstimulation
AT duwei rebuildingmotorfunctionofthespinalcordbasedonfunctionalelectricalstimulation
AT huangwei rebuildingmotorfunctionofthespinalcordbasedonfunctionalelectricalstimulation
AT chenyi rebuildingmotorfunctionofthespinalcordbasedonfunctionalelectricalstimulation