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5′-Inositol phosphatase SHIP2 recruits Mena to stabilize invadopodia for cancer cell invasion
Invadopodia are specialized membrane protrusions that support degradation of extracellular matrix (ECM) by cancer cells, allowing invasion and metastatic spread. Although early stages of invadopodia assembly have been elucidated, little is known about maturation of invadopodia into structures compet...
Autores principales: | Rajadurai, Charles V., Havrylov, Serhiy, Coelho, Paula P., Ratcliffe, Colin D.H., Zaoui, Kossay, Huang, Bruce H., Monast, Anie, Chughtai, Naila, Sangwan, Veena, Gertler, Frank B., Siegel, Peter M., Park, Morag |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021089/ https://www.ncbi.nlm.nih.gov/pubmed/27597754 http://dx.doi.org/10.1083/jcb.201501003 |
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