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Spatiotemporal analysis of putative notochordal cell markers reveals CD24 and keratins 8, 18, and 19 as notochord‐specific markers during early human intervertebral disc development
In humans, the nucleus pulposus (NP) is composed of large vacuolated notochordal cells in the fetus but, soon after birth, becomes populated by smaller, chondrocyte‐like cells. Although animal studies indicate that notochord‐derived cells persist in the adult NP, the ontogeny of the adult human NP c...
Autores principales: | Rodrigues‐Pinto, Ricardo, Berry, Andrew, Piper‐Hanley, Karen, Hanley, Neil, Richardson, Stephen M., Hoyland, Judith A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021113/ https://www.ncbi.nlm.nih.gov/pubmed/26910849 http://dx.doi.org/10.1002/jor.23205 |
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