Genome-Wide Assessment of Efficiency and Specificity in CRISPR/Cas9 Mediated Multiple Site Targeting in Arabidopsis

Simultaneous multiplex mutation of large gene families using Cas9 has the potential to revolutionize agriculture and plant sciences. The targeting of multiple genomic sites at once raises concerns about the efficiency and specificity in targeting. The model Arabidopsis thaliana is widely used in bas...

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Detalles Bibliográficos
Autores principales: Peterson, Brenda A., Haak, David C., Nishimura, Marc T., Teixeira, Paulo J. P. L., James, Sean R., Dangl, Jeffery L., Nimchuk, Zachary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021288/
https://www.ncbi.nlm.nih.gov/pubmed/27622539
http://dx.doi.org/10.1371/journal.pone.0162169

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