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Benzylglucosinolate Derived Isothiocyanate from Tropaeolum majus Reduces Gluconeogenic Gene and Protein Expression in Human Cells

Nasturtium (Tropaeolum majus L.) contains high concentrations of benzylglcosinolate. We found that a hydrolysis product of benzyl glucosinolate—the benzyl isothiocyanate (BITC)—modulates the intracellular localization of the transcription factor Forkhead box O 1 (FOXO1). FoxO transcription factors c...

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Detalles Bibliográficos
Autores principales: Guzmán-Pérez, Valentina, Bumke-Vogt, Christiane, Schreiner, Monika, Mewis, Inga, Borchert, Andrea, Pfeiffer, Andreas F. H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021297/
https://www.ncbi.nlm.nih.gov/pubmed/27622707
http://dx.doi.org/10.1371/journal.pone.0162397