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Delta/Notch-Like EGF-Related Receptor (DNER) Is Not a Notch Ligand

Delta/Notch-like EGF-related receptor (DNER) has been reported to act as a Notch ligand, despite lacking a Delta/Serrate/Lag (DSL) binding domain common to all other known ligands. The established Notch ligand Delta-like 1 (DLL1), but not DNER, activated Notch1 in a luciferase assay, prevented the d...

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Detalles Bibliográficos
Autores principales:	Greene, Maxwell, Lai, Yongjie, Pajcini, Kostandin, Bailis, Will, Pear, Warren S., Lancaster, Eric
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021350/ https://www.ncbi.nlm.nih.gov/pubmed/27622512 http://dx.doi.org/10.1371/journal.pone.0161157

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