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Self-Organizing 3D Human Neural Tissue Derived from Induced Pluripotent Stem Cells Recapitulate Alzheimer’s Disease Phenotypes

The dismal success rate of clinical trials for Alzheimer’s disease (AD) motivates us to develop model systems of AD pathology that have higher predictive validity. The advent of induced pluripotent stem cells (iPSCs) allows us to model pathology and study disease mechanisms directly in human neural...

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Detalles Bibliográficos
Autores principales:	Raja, Waseem K., Mungenast, Alison E., Lin, Yuan-Ta, Ko, Tak, Abdurrob, Fatema, Seo, Jinsoo, Tsai, Li-Huei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021368/ https://www.ncbi.nlm.nih.gov/pubmed/27622770 http://dx.doi.org/10.1371/journal.pone.0161969

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