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Improved Efficiency and Reliability of NGS Amplicon Sequencing Data Analysis for Genetic Diagnostic Procedures Using AGSA Software

Screening for BRCA mutations in women with familial risk of breast or ovarian cancer is an ideal situation for high-throughput sequencing, providing large amounts of low cost data. However, 454, Roche, and Ion Torrent, Thermo Fisher, technologies produce homopolymer-associated indel errors, complica...

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Detalles Bibliográficos
Autores principales:	Poulet, Axel, Privat, Maud, Ponelle, Flora, Viala, Sandrine, Decousus, Stephanie, Perin, Axel, Lafarge, Laurence, Ollier, Marie, El Saghir, Nagi S., Uhrhammer, Nancy, Bignon, Yves-Jean, Bidet, Yannick
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021467/ https://www.ncbi.nlm.nih.gov/pubmed/27656653 http://dx.doi.org/10.1155/2016/5623089

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