Male-lineage transmission of an acquired metabolic phenotype induced by grand-paternal obesity

OBJECTIVE: Parental obesity can induce metabolic phenotypes in offspring independent of the inherited DNA sequence. Here we asked whether such non-genetic acquired metabolic traits can be passed on to a second generation that has never been exposed to obesity, even as germ cells. METHODS: We examine...

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Detalles Bibliográficos
Autores principales: Cropley, Jennifer E., Eaton, Sally A., Aiken, Alastair, Young, Paul E., Giannoulatou, Eleni, Ho, Joshua W.K., Buckland, Michael E., Keam, Simon P., Hutvagner, Gyorgy, Humphreys, David T., Langley, Katherine G., Henstridge, Darren C., Martin, David I.K., Febbraio, Mark A., Suter, Catherine M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Brief Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021672/
https://www.ncbi.nlm.nih.gov/pubmed/27656407
http://dx.doi.org/10.1016/j.molmet.2016.06.008

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