Cargando…

Amyloidogenic amyloid-β-peptide variants induce microbial agglutination and exert antimicrobial activity

Amyloid-β (Aβ) peptides are the main components of the plaques found in the brains of patients with Alzheimer’s disease. However, Aβ peptides are also detectable in secretory compartments and peripheral blood contains a complex mixture of more than 40 different modified and/or N- and C-terminally tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Spitzer, Philipp, Condic, Mateja, Herrmann, Martin, Oberstein, Timo Jan, Scharin-Mehlmann, Marina, Gilbert, Daniel F., Friedrich, Oliver, Grömer, Teja, Kornhuber, Johannes, Lang, Roland, Maler, Juan Manuel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5021948/ https://www.ncbi.nlm.nih.gov/pubmed/27624303 http://dx.doi.org/10.1038/srep32228

Ejemplares similares

Analysis of Surface Levels of IL-1 Receptors and Macrophage Scavenger Receptor I in Peripheral Immune Cells of Patients With Alzheimer Disease
por: Spitzer, Philipp, et al.
Publicado: (2019)

Pharmacological Inhibition of Amyloidogenic APP Processing and Knock-Down of APP in Primary Human Macrophages Impairs the Secretion of Cytokines
por: Spitzer, Philipp, et al.
Publicado: (2020)

Imbalance of Circulating T(h)17 and Regulatory T Cells in Alzheimer’s Disease: A Case Control Study
por: Oberstein, Timo Jan, et al.
Publicado: (2018)

Cerebrospinal Fluid of Patients With Alzheimer’s Disease Contains Increased Percentages of Synaptophysin-Bearing Microvesicles
por: Utz, Janine, et al.
Publicado: (2021)

Microvesicles from cerebrospinal fluid of patients with Alzheimer’s disease display reduced concentrations of tau and APP protein
por: Spitzer, Philipp, et al.
Publicado: (2019)

A Specific Reduction in Aβ(1−42) vs. a Universal Loss of Aβ Peptides in CSF Differentiates Alzheimer's Disease From Meningitis and Multiple Sclerosis
por: Spitzer, Philipp, et al.
Publicado: (2018)

Amyloid-β levels and cognitive trajectories in non-demented pTau181-positive subjects without amyloidopathy
por: Oberstein, Timo Jan, et al.
Publicado: (2022)

Amyloid peptides with antimicrobial and/or microbial agglutination activity
por: Chen, Dongru, et al.
Publicado: (2022)

The Role of Cathepsin B in the Degradation of Aβ and in the Production of Aβ Peptides Starting With Ala2 in Cultured Astrocytes
por: Oberstein, Timo Jan, et al.
Publicado: (2021)

Spot quantification in two dimensional gel electrophoresis image analysis: comparison of different approaches and presentation of a novel compound fitting algorithm
por: Brauner, Jan M, et al.
Publicado: (2014)

Reconceptualization of the Erlangen Score for the Assessment of Dementia Risk: The ERlangen Score
por: Utz, Janine, et al.
Publicado: (2023)

Phagocytosis and LPS alter the maturation state of β-amyloid precursor protein and induce different Aβ peptide release signatures in human mononuclear phagocytes
por: Spitzer, Philipp, et al.
Publicado: (2010)

Nano- and Micro-Patterned S-, H-, and X-PDMS for Cell-Based Applications: Comparison of Wettability, Roughness, and Cell-Derived Parameters
por: Scharin-Mehlmann, Marina, et al.
Publicado: (2018)

Neurogranin and YKL-40: independent markers of synaptic degeneration and neuroinflammation in Alzheimer’s disease
por: Hellwig, Konstantin, et al.
Publicado: (2015)

Digit Ratio (2D:4D) Is Not Associated with Alzheimer’s Disease in the Elderly
por: Siegmann, Eva-Maria, et al.
Publicado: (2023)

Cerebrospinal fluid biomarkers for cerebral amyloid angiopathy
por: Sembill, Jochen A, et al.
Publicado: (2023)

Multifaceted anti-amyloidogenic and pro-amyloidogenic effects of C-reactive protein and serum amyloid P component in vitro
por: Ozawa, Daisaku, et al.
Publicado: (2016)

PASSED: Brain atrophy in non-demented individuals in a long-term longitudinal study from two independent cohorts
por: Haas, Anna-Lena, et al.
Publicado: (2023)

Cooperativity among Short Amyloid Stretches in Long Amyloidogenic Sequences
por: Hu, Lele, et al.
Publicado: (2012)

Effects of Intramolecular Distance between Amyloidogenic Domains on Amyloid Aggregation
por: Ko, Ahra, et al.
Publicado: (2012)

Mechanism of Amyloid Gel Formation by Several Short Amyloidogenic Peptides
por: Galzitskaya, Oxana V., et al.
Publicado: (2021)

STUDIES IN AGGLUTINATION : III. ON THE MECHANISM OF THE AGGLUTINATION OF BACTERIA BY SPECIFIC AGGLUTINATING SERUM.
por: Shibley, Gerald S.
Publicado: (1926)

STUDIES IN AGGLUTINATION : I. THE AGGLUTINATION OF STREPTOCOCCI.
por: Shibley, Gerald S.
Publicado: (1924)

Amyloidogenicity and toxicity of the reverse and scrambled variants of amyloid‐β 1‐42
por: Vadukul, Devkee M., et al.
Publicado: (2017)

Lack of N-glycosylation increases amyloidogenic processing of the amyloid precursor protein
por: Lin, Tong, et al.
Publicado: (2022)

Pharmacist-Led Medication Reviews to Identify and Collaboratively Resolve Drug-Related Problems in Psychiatry – A Controlled, Clinical Trial
por: Wolf, Carolin, et al.
Publicado: (2015)

STUDIES IN AGGLUTINATION : IV. THE AGGLUTINATION INHIBITION ZONE
por: Shibley, Gerald S.
Publicado: (1929)

Structural Similarities and Differences between Amyloidogenic and Non-Amyloidogenic Islet Amyloid Polypeptide (IAPP) Sequences and Implications for the Dual Physiological and Pathological Activities of These Peptides
por: Wu, Chun, et al.
Publicado: (2013)

Amyloidogenic processing of the Alzheimer β-amyloid precursor protein depends on lipid rafts
por: Ehehalt, Robert, et al.
Publicado: (2003)

SIRT3 activator Honokiol attenuates β-Amyloid by modulating amyloidogenic pathway
por: Ramesh, Sindhu, et al.
Publicado: (2018)

AGGLUTINATION BY PRECIPITIN
por: Jones, F. S.
Publicado: (1927)

Agglutination Reactions
por: Love, Andrew
Publicado: (1908)

Evolvability of Amyloidogenic Proteins in Human Brain
por: Hashimoto, Makoto, et al.
Publicado: (2018)

On the border of the amyloidogenic sequences: prefix analysis of the parallel beta sheets in the PDB_Amyloid collection
por: Takács, Kristóf, et al.
Publicado: (2021)

Structural characterisation of amyloid-like fibrils formed by an amyloidogenic peptide segment of β-lactoglobulin
por: Gowda, Vasantha, et al.
Publicado: (2021)

AMPA Receptor Activation Promotes Non-Amyloidogenic Amyloid Precursor Protein Processing and Suppresses Neuronal Amyloid-β Production
por: Hoey, Sarah E., et al.
Publicado: (2013)

O-GlcNAcylation increases non-amyloidogenic processing of the amyloid-β precursor protein (APP)
por: Jacobsen, Kristin, et al.
Publicado: (2013)

Extremely Amyloidogenic Single-Chain Analogues of Insulin’s H-Fragment: Structural Adaptability of an Amyloid Stretch
por: Dec, Robert, et al.
Publicado: (2020)

The orphan drug dichloroacetate reduces amyloid beta-peptide production whilst promoting non-amyloidogenic proteolysis of the amyloid precursor protein
por: Parkin, Edward T., et al.
Publicado: (2022)

Depression and attempted suicide under pregabalin therapy
por: Kustermann, Andreas, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g4rg81t7o2agf3erc894adlc42